Saur Anaïs, Koessler Thibaud, Astaras Christoforos
Service d'oncologie médicale, Département d'oncologie, HUG, 1211 Genève 14.
Swiss Cancer Center Léman, AGORA, Pôle de recherche sur le cancer, 1005 Lausanne.
Rev Med Suisse. 2021 May 19;17(739):979-984.
Digestive tumors account for a quarter of all new cancer cases diagnosed worldwide and are responsible for a third of global cancer-related deaths. Immunotherapy with immune checkpoint inhibitors has recently shown its effectiveness in the therapeutic arsenal of these tumors, mainly in the advanced stages. This article summarizes the current indications and the future direction of immunotherapy in patients with digestive malignancies.
消化系统肿瘤占全球新诊断癌症病例的四分之一,且导致全球三分之一的癌症相关死亡。免疫检查点抑制剂免疫疗法最近在这些肿瘤的治疗手段中显示出了有效性,主要用于晚期。本文总结了免疫疗法在消化系统恶性肿瘤患者中的当前适应证及未来方向。