Am J Epidemiol. 2021 Nov 2;190(11):2350-2359. doi: 10.1093/aje/kwab148.
It is unknown whether people in same-sex relationships who give birth have different perinatal outcomes than people in different-sex relationships, despite differences in risk factors such as use of assisted reproductive technologies, obesity, smoking, and poor mental health. Marriage equality has established birth certificates as a promising new source of population-based data on births to same-sex married parents. We used birth certificate data from Massachusetts for 201,873 singletons born to married parents from 2012 to 2016. We estimated the associations of several birth outcomes with having a birth parent in a same-sex marriage using propensity score-matched and -unmatched samples. We also tested whether these associations were modified by the use of assisted reproductive technologies. People in same-sex marriages who gave birth had perinatal outcomes related to decreased fetal growth and preterm birth that were similar to those of their peers in different-sex marriages. Use of assisted reproductive technology was associated with decreased fetal growth and increased risk of preterm birth for infants with different-sex parents but not for infants with same-sex parents. More research is needed across other states and to understand why use of assisted reproductive technology is not a risk factor for poor birth outcomes for those in same-sex marriages.
尽管在辅助生殖技术、肥胖、吸烟和心理健康状况不佳等风险因素方面存在差异,但同性关系中生育的人与异性关系中生育的人在围产期结局方面是否存在差异尚不清楚。婚姻平等使出生证明成为了一种有前途的新的基于人群的同性已婚父母生育数据来源。我们使用了马萨诸塞州 2012 年至 2016 年期间 201,873 名已婚父母所生的单胎出生证明数据。我们使用倾向评分匹配和未匹配样本,估计了几种出生结局与出生父母同性婚姻之间的关联。我们还测试了这些关联是否会因辅助生殖技术的使用而发生变化。同性婚姻中生育的人在胎儿生长和早产方面的围产期结局与异性婚姻中的同龄人相似。辅助生殖技术的使用与胎儿生长减少和具有异性父母的婴儿早产风险增加有关,但与具有同性父母的婴儿无关。需要在其他州进行更多研究,以了解为什么辅助生殖技术的使用不是同性婚姻中不良生育结局的风险因素。