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创伤性脊髓疾病:当前的主题和未来的方向。

Traumatic Spinal Cord Disorders: Current Topics and Future Directions.

机构信息

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

出版信息

Semin Neurol. 2021 Jun;41(3):247-255. doi: 10.1055/s-0041-1725125. Epub 2021 May 19.

DOI:10.1055/s-0041-1725125
PMID:34010969
Abstract

Traumatic spinal cord injury (tSCI) is a life-changing and potentially overwhelming event. The sudden disruption of the spinal cord's integrity necessitates rapid attention at a specialized medical center, and involves a multilateral collaboration between neurologists, spine surgeons, critical care physicians, and trauma specialists. Even with care under ideal conditions, many tSCI patients have significant disability that persists for the rest of their lives. However, recently, we have seen a proliferation in clinical and translational trials that offer the promise that new treatments may be available soon.

摘要

创伤性脊髓损伤(tSCI)是一个改变生活且可能令人难以承受的事件。脊髓完整性的突然中断需要在专门的医疗中心迅速关注,并涉及神经科医生、脊柱外科医生、重症监护医生和创伤专家之间的多边合作。即使在理想条件下进行治疗,许多 tSCI 患者仍有严重的残疾,这种残疾会伴随他们的余生。然而,最近,我们看到了越来越多的临床和转化试验,这些试验带来了新的治疗方法可能很快就会问世的希望。

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Front Genet. 2025 Jul 2;16:1609439. doi: 10.3389/fgene.2025.1609439. eCollection 2025.
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Effectiveness of Hydrotherapy on Neuropathic Pain and Pain Catastrophization in Patients With Spinal Cord Injury: Protocol for a Pilot Trial Study.水疗法对脊髓损伤患者神经性疼痛和疼痛灾难化的疗效:一项试点试验研究方案
JMIR Res Protoc. 2022 Apr 29;11(4):e37255. doi: 10.2196/37255.
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Neuroinflammation and Scarring After Spinal Cord Injury: Therapeutic Roles of MSCs on Inflammation and Glial Scar.
脊髓损伤后的神经炎症和瘢痕形成:间充质干细胞在炎症和神经胶质瘢痕中的治疗作用。
Front Immunol. 2021 Dec 2;12:751021. doi: 10.3389/fimmu.2021.751021. eCollection 2021.