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[联合颞下窝入路在岩骨内颈动脉重建治疗大型侧颅底肿瘤中的临床应用]

[Clinical application of combined infratemporal fossa approaches for internal carotid artery in petrous bone reconstruction for large lateral skull base tumors].

作者信息

Feng G D, Wei X M, Zheng Y H, Zhang T, Tian X, Zhao Y, Zhou Y L, Gao Z Q

机构信息

Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 May 7;56(5):417-423. doi: 10.3760/cma.j.cn115330-20200613-00500.

Abstract

By summarizing the technical points and therapeutic outcomes of combing infratemporal fossa approach (IFA) and internal carotid artery (ICA) reconstruction for the colossal skull base tumor invading ICA in petrous bone, the clinical application value was discussed. Five patients (2 males, 3 females,aging from 27 to 55 years old) who received surgeries between July 2015 and May 2017 for lateral skull base pathology involved petrous ICA using technique combined IFA and pre-reconstruction, were reviewed. Among the five patients, three were paraganglioma of head and neck, one was carotid aneurysms, and one was recurrent adenoid cystic carcinoma (ACC). The median tumor size in the largest cross-section was 60 mm × 51 mm (range, 28 mm × 22 mm-72 mm × 58 mm). Complete excision was achieved with IFA and ICA reconstruction. The median blood loss volume was 1 000 ml (range, 600-2 500 ml). Four cases showed no new long-term neurologic sequelae, while one showed hemiplegia due to graft vessel occlusion. Except for the one with ACC having facial nerve cut, others achieved good facial nerve function of HB grade Ⅰ to Ⅱ during 3 to 12 months, follow-up. No tumor recurrence was observed over the median duration of follow-up for above 36 months (range, 36-58 months). For lesions involved superior part of ICA, which is unable to separate from ICA, IFA and ICA reconstruction can achieve complete excision.

摘要

通过总结颞下窝入路(IFA)联合颈内动脉(ICA)重建术治疗侵犯岩骨ICA的巨大颅底肿瘤的技术要点和治疗效果,探讨其临床应用价值。回顾性分析2015年7月至2017年5月期间接受手术治疗的5例累及岩骨段ICA的侧颅底病变患者(2例男性,3例女性,年龄27至55岁),采用IFA联合预重建技术。5例患者中,3例为头颈部副神经节瘤,1例为颈动脉动脉瘤,1例为复发性腺样囊性癌(ACC)。最大横截面肿瘤中位数大小为60 mm×51 mm(范围28 mm×22 mm - 72 mm×58 mm)。通过IFA和ICA重建实现了肿瘤全切。术中中位数失血量为1000 ml(范围600 - 2500 ml)。4例患者未出现新的长期神经功能后遗症,1例因移植血管闭塞出现偏瘫。除1例ACC患者面神经切断外,其他患者在3至12个月的随访期间面神经功能恢复良好,HB分级为Ⅰ至Ⅱ级。在中位随访时间超过36个月(范围36 - 58个月)内未观察到肿瘤复发。对于累及ICA上部且无法与ICA分离的病变,IFA联合ICA重建可实现肿瘤全切。

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