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脊髓刺激器治疗因横贯性脊髓炎导致严重残疾的神经性疼痛患者。

Spinal cord stimulator for neuropathic pain in a patient with severe disability due to transverse myelitis.

机构信息

Anesthesiology, Eugenio Espejo Hospital of Specialties, Quito, Pichincha, Ecuador.

Teaching and Research, Eugenio Espejo Hospital of Specialties, Pichincha, Quito, Ecuador

出版信息

BMJ Case Rep. 2021 May 19;14(5):e242522. doi: 10.1136/bcr-2021-242522.

DOI:10.1136/bcr-2021-242522
PMID:34011645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8137221/
Abstract

Transverse myelitis is an inflammatory disease of the central nervous system that disrupts nerve signals' conduction. The illness is characterised by weakness in the lower limbs accompanied by paresthesia and urinary and bowel incontinence. The most disabling sequel is the onset of chronic neuropathic pain, which can severely limit the patient's independence and negatively affect her quality of life. We present the case of a patient who received a spinal neurostimulator after a failure of conventional medical treatment. Masking pain through paresthesia, a mechanism provided by the device significantly reduces pain perception. The treatment success in our patient represents an advance in pain therapy.

摘要

横断性脊髓炎是一种中枢神经系统炎症性疾病,会破坏神经信号的传导。该病的特征是下肢无力,伴有感觉异常以及尿便失禁。最致残的后果是出现慢性神经性疼痛,这可能严重限制患者的独立性并对其生活质量产生负面影响。我们报告了一例患者,在常规药物治疗失败后接受了脊髓神经刺激器治疗。通过设备提供的感觉异常来掩盖疼痛,这一机制显著降低了疼痛感知。我们的患者治疗成功代表了疼痛治疗的一项进展。

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Spinal cord stimulator for neuropathic pain in a patient with severe disability due to transverse myelitis.脊髓刺激器治疗因横贯性脊髓炎导致严重残疾的神经性疼痛患者。
BMJ Case Rep. 2021 May 19;14(5):e242522. doi: 10.1136/bcr-2021-242522.
2
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A A Pract. 2019 Dec 1;13(11):409-412. doi: 10.1213/XAA.0000000000001078.
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本文引用的文献

1
Relief of Neuropathic Pain After Spinal Cord Stimulator Implantation in a Patient With Idiopathic Thoracic Transverse Myelitis: A Case Report.特发性胸段横贯性脊髓炎患者植入脊髓刺激器后神经性疼痛缓解:病例报告
A A Pract. 2019 Dec 1;13(11):409-412. doi: 10.1213/XAA.0000000000001078.
2
Scrambler Therapy for Treatment-Resistant Central Neuropathic Pain in a Patient with Transverse Myelitis.扰频器疗法治疗横贯性脊髓炎患者的难治性中枢神经性疼痛
Int J MS Care. 2019 Mar-Apr;21(2):76-80. doi: 10.7224/1537-2073.2017-083.
3
EAN guidelines on central neurostimulation therapy in chronic pain conditions.欧洲神经病学学会(EAN)关于慢性疼痛病症中枢神经刺激疗法的指南。
Eur J Neurol. 2016 Oct;23(10):1489-99. doi: 10.1111/ene.13103. Epub 2016 Aug 11.
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Spinal cord stimulation: Current applications for treatment of chronic pain.脊髓刺激:治疗慢性疼痛的当前应用
Anesth Essays Res. 2011 Jan-Jun;5(1):20-7. doi: 10.4103/0259-1162.84174.
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Clinical practice. Transverse myelitis.临床实践。横贯性脊髓炎。
N Engl J Med. 2010 Aug 5;363(6):564-72. doi: 10.1056/NEJMcp1001112.
6
Spinal cord stimulator relieves neuropathic pain in a patient with radiation-induced transverse myelitis.脊髓刺激器缓解了一名放射性横贯性脊髓炎患者的神经性疼痛。
Pain Pract. 2007 Dec;7(4):345-7. doi: 10.1111/j.1533-2500.2007.00148.x. Epub 2007 Nov 6.
7
Safety and efficacy of spinal cord stimulation for the treatment of chronic pain: a 20-year literature review.脊髓刺激治疗慢性疼痛的安全性与有效性:一项20年的文献综述
J Neurosurg. 2004 Mar;100(3 Suppl Spine):254-67. doi: 10.3171/spi.2004.100.3.0254.
8
Transverse Myelitis: pathogenesis, diagnosis and treatment.横贯性脊髓炎:发病机制、诊断与治疗
Front Biosci. 2004 May 1;9:1483-99. doi: 10.2741/1351.
9
Efficacy of spinal cord stimulation for neuropathic pain following idiopathic acute transverse myelitis: a case report.脊髓刺激治疗特发性急性横贯性脊髓炎后神经性疼痛的疗效:一例报告
Clin Neurol Neurosurg. 1999 Jun;101(2):125-7. doi: 10.1016/s0303-8467(99)00012-8.