Liu Ya-Meng, Hu Die, Zhou Long-Fang, Lan Jie, Feng Cheng-Cheng, Wang Xiao-Yun, Pan Xiao-Jing
Weifang Medical University, Weifang 261021, Shandong Province, China.
State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, Qingdao 266071, Shandong Province, China.
Int J Ophthalmol. 2021 May 18;14(5):714-718. doi: 10.18240/ijo.2021.05.11. eCollection 2021.
To investigate the association of axial length (AL), lens thickness (LT), and lens vault (LV) with postoperative anterior chamber angle metrics after laser peripheral iridotomy (LPI).
Prospective observational study of 69 patients (97 eyes) were diagnosed as primary angle-closure suspect (PACS), primary angle closure (PAC) or primary angle-closure glaucoma (PACG). AL, LT, anterior central chamber depth (ACD), angle opening distance (AOD), trabecular iris angle (TIA), and angle recess area (ARA) were measured before and 1wk after LPI. The association between AL, LT, LV with ACD, AOD, TIA, ARA were analyzed by comparing the differences between preoperative and postoperative measurements for anterior segment biometric parameters.
ACD, AOD, TIA, and ARA were significantly increased after LPI (all <0.05). Greater LT was significantly associated with greater postoperative increases in ACD, AOD, TIA, and ARA (all <0.05). AL was not significantly associated with changes of anterior segment biometric parameters. Greater LV was significantly associated with greater postoperative increases in ACD, AOD, and TIA (all <0.05), but was not significantly associated with changes of ARA.
Greater baseline LT and LV measurements are associated with greater increases in anterior segment biometric parameters after laser peripheral iridotomy. AL are not associated with the change of anterior segment biometric parameters.
探讨眼轴长度(AL)、晶状体厚度(LT)和晶状体拱高(LV)与激光周边虹膜切开术(LPI)术后前房角参数的相关性。
对69例患者(97只眼)进行前瞻性观察研究,这些患者被诊断为原发性房角关闭可疑(PACS)、原发性房角关闭(PAC)或原发性闭角型青光眼(PACG)。在LPI术前和术后1周测量AL、LT、中央前房深度(ACD)、房角开放距离(AOD)、小梁虹膜夹角(TIA)和房角隐窝面积(ARA)。通过比较眼前节生物测量参数术前和术后测量值的差异,分析AL、LT、LV与ACD、AOD、TIA、ARA之间的相关性。
LPI术后ACD、AOD、TIA和ARA均显著增加(均P<0.05)。LT越大,术后ACD、AOD、TIA和ARA的增加越显著(均P<0.05)。AL与眼前节生物测量参数的变化无显著相关性。LV越大,术后ACD、AOD和TIA的增加越显著(均P<0.05),但与ARA的变化无显著相关性。
基线LT和LV测量值越大,激光周边虹膜切开术后眼前节生物测量参数的增加越大。AL与眼前节生物测量参数的变化无关。