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ASA 评分可预测髋部骨折后感染、心血管并发症和再次住院率——一项全国性队列研究。

The ASA score predicts infections, cardiovascular complications, and hospital readmissions after hip fracture - A nationwide cohort study.

机构信息

Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, SE-17177, Stockholm, Sweden.

Department of Clinical Science, Intervention and Technology (CLINTEC) Karolinska Institutet, SE-17177, Stockholm, Sweden.

出版信息

Osteoporos Int. 2021 Nov;32(11):2185-2192. doi: 10.1007/s00198-021-05956-w. Epub 2021 May 19.

Abstract

UNLABELLED

This study examines the association between the ASA physical status classification score at hip fracture surgery and severe postoperative complications in patients aged 60 and older. Among both men and women, ASA scores consistently predict a wide range of complications including infections, cardiovascular complications, hospital readmissions, and death.

INTRODUCTION

Hip fractures are common in aging populations and associated with poor prognosis. This study examines how the American Society of Anaesthesiologists (ASA) physical status classification is related to severe complications among hip fracture patients including infections, cardiovascular diseases, hospital readmissions, and death.

METHODS

Based on a linkage of the Swedish National Inpatient Register with the Swedish National Registry for Hip Fractures (RIKSHÖFT), this study includes patients aged 60+ with first hip fracture between 1998 and 2017. We estimated associations between ASA score and complications during the hospital stay and during 1 year after hip fracture using multivariable-adjusted logistic regression and Cox proportional hazard regression.

RESULTS

The study population included 170,193 hip fracture patients of which 24% died and 39% were readmitted to hospital within 1 year. The most common complications were urinary tract infections, pneumonia, second hip fractures, and heart failure. Among both men and women, higher ASA scores were consistently associated with higher risks for all complications included in this study. The strongest associations were observed for heart failure, myocardial infarction, pneumonia, and death.

CONCLUSION

ASA scores are routinely assessed in clinical practice and predict a wide range of postoperative complications among hip fracture patients. Since many complications may be preventable through adequate drug treatment, rehabilitation, and risk awareness, future studies should examine the mechanisms linking ASA scores to complication risk in order to improve preventive strategies. Particularly, the high risk of cardiovascular complications among patients with high ASA scores deserves clinical and scientific attention.

摘要

本研究探讨了美国麻醉医师协会(ASA)身体状况分类评分与 60 岁及以上髋部骨折患者术后严重并发症之间的关系。在男性和女性中,ASA 评分始终预测包括感染、心血管并发症、医院再入院和死亡在内的广泛并发症。

简介

髋部骨折在老年人群中很常见,且预后不良。本研究探讨了美国麻醉医师协会(ASA)身体状况分类与髋部骨折患者的严重并发症(包括感染、心血管疾病、医院再入院和死亡)之间的关系。

方法

基于瑞典国家住院患者登记处与瑞典髋部骨折国家登记处(RIKSHÖFT)的链接,本研究纳入了 1998 年至 2017 年间首次发生髋部骨折的年龄在 60 岁及以上的患者。我们使用多变量调整的逻辑回归和 Cox 比例风险回归估计了 ASA 评分与住院期间和髋部骨折后 1 年内并发症之间的关联。

结果

研究人群包括 170193 例髋部骨折患者,其中 24%死亡,39%在 1 年内再次入院。最常见的并发症是尿路感染、肺炎、再次发生髋部骨折和心力衰竭。在男性和女性中,较高的 ASA 评分与本研究纳入的所有并发症的风险增加均相关。最强的关联见于心力衰竭、心肌梗死、肺炎和死亡。

结论

ASA 评分在临床实践中常规评估,并预测髋部骨折患者术后广泛的并发症。由于许多并发症可以通过充分的药物治疗、康复和风险意识来预防,因此未来的研究应探讨 ASA 评分与并发症风险之间的联系机制,以改进预防策略。特别是,高 ASA 评分患者的心血管并发症风险较高,值得临床和科学关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98ad/8563539/8e9e879e1db6/198_2021_5956_Fig1_HTML.jpg

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