Karampampa Korinna, Ahlbom Anders, Michaëlsson Karl, Andersson Tomas, Drefahl Sven, Modig Karin
Institute of Environmental Medicine, Unit of Epidemiology, Karolinska Institutet, Stockholm, Sweden.
Institute of Environmental Medicine, Unit of Epidemiology, Karolinska Institutet, Stockholm, Sweden; Centre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden.
Bone. 2015 Sep;78:55-61. doi: 10.1016/j.bone.2015.04.032. Epub 2015 Apr 28.
Hip fracture is a common cause of disability and mortality among the elderly. Declining incidence trends have been observed in Sweden. Still, this condition remains a significant public health problem since Sweden has one of the highest incidences worldwide. Yet, no Swedish lifetime risk or survival trends have been presented. By examining how hip fracture incidence, post-fracture survival, as well as lifetime risk have developed between 1995 and 2010 in Sweden, this study aims to establish how the burden hip fractures pose on the elderly changed over time, in order to inform initiatives for improvements of their health.
The entire Swedish population 60 years-old and above was followed between 1987 and 2010 in the National Patient Register and the Cause of Death Register. Annual age-specific hip fracture cumulative incidence was estimated using hospital admissions for hip fractures. Three-month and one-year survival after the first hip fracture were also estimated. Period life table was used to assess lifetime risk of hip fractures occurring from age 60 and above, and the expected mean age of the first hip fracture.
The age-specific hip fracture incidence decreased between 1995 and 2010 in all ages up to 94 years, on average by 1% per year. The lifetime risk remained almost stable, between 9% and 11% for men, and between 18% and 20% for women. The expected mean age of a first hip fracture increased by 2.5 years for men and by 2.2 years for women. No improvements over time were observed for the 3-month survival for men, while for women a 1% decrease per year was observed. The 1-year survival slightly increased over time for men (0.4% per year) while no improvement was observed for women.
The age-specific hip fracture incidence has decreased over time. Yet the lifetime risk of a hip fracture has not decreased because life expectancy in the population has increased in parallel. Overall, survival after hip fracture has not improved.
髋部骨折是老年人残疾和死亡的常见原因。瑞典已观察到发病率呈下降趋势。然而,由于瑞典是全球发病率最高的国家之一,这种情况仍然是一个重大的公共卫生问题。不过,瑞典尚未公布终生风险或生存趋势。通过研究1995年至2010年期间瑞典髋部骨折发病率、骨折后生存率以及终生风险的变化情况,本研究旨在确定髋部骨折给老年人带来的负担如何随时间变化,以便为改善他们健康状况的举措提供信息。
1987年至2010年期间,在国家患者登记册和死亡原因登记册中对瑞典全体60岁及以上人口进行了跟踪。使用髋部骨折的住院记录估算每年特定年龄的髋部骨折累积发病率。还估算了首次髋部骨折后的三个月和一年生存率。采用时期生命表评估60岁及以上人群发生髋部骨折的终生风险以及首次髋部骨折的预期平均年龄。
1995年至2010年期间,94岁及以下各年龄段的特定年龄髋部骨折发病率均有所下降,平均每年下降1%。终生风险几乎保持稳定,男性为9%至11%,女性为18%至20%。男性首次髋部骨折的预期平均年龄增加了2.5岁,女性增加了2.2岁。男性的三个月生存率未随时间改善,而女性每年下降1%。男性的一年生存率随时间略有增加(每年0.4%),而女性未观察到改善。
特定年龄的髋部骨折发病率随时间下降。然而,髋部骨折的终生风险并未降低,因为同期人口预期寿命有所增加。总体而言,髋部骨折后的生存率并未提高。