Mäntysaari M J, Antila K J, Peltonen T E
Cardiorespiratory Research Unit, University of Turku, Finland.
Am J Hypertens. 1988 Apr;1(2):132-9. doi: 10.1093/ajh/1.2.132.
The hemodynamic reactions of 30 young men with neurocirculatory asthenia (NCA) were compared to those of 30 healthy controls in isometric handgrip test, orthostatic test, and cold pressor test in order to study the regulation of the central circulation of NCA patients. The measurements were made using sphygmomanometry, ECG, and impedance cardiography. In the isometric handgrip test the heart rate and the diastolic and mean blood pressure increased slightly more (P less than 0.05) in the NCA group than in the controls. In the NCA group the blood pressure rise was, on average, due to an increase in the peripheral vascular resistance, while in the control group it was caused by an elevation in the cardiac output. In the orthostatic and cold pressor tests the hemodynamic alterations were quite similar in the two groups. It is concluded that the NCA patients have in the orthostatic and cold pressor tests a normal ability to elevate the blood pressure by increasing the peripheral vascular resistance. The lack of rise in the cardiac output during the isometric handgrip test in the NCA group is an abnormal reaction, the reason of which remains to be studied.
为研究神经循环无力症（NCA）患者的中枢循环调节情况，将30名患有神经循环无力症的年轻男性与30名健康对照者在等长握力试验、直立试验和冷加压试验中的血流动力学反应进行了比较。测量采用了血压计、心电图和阻抗心动图。在等长握力试验中，NCA组的心率、舒张压和平均血压升高幅度略大于对照组（P小于0.05）。在NCA组，血压升高平均是由于外周血管阻力增加，而对照组则是由于心输出量增加。在直立试验和冷加压试验中，两组的血流动力学改变相当相似。结论是，NCA患者在直立试验和冷加压试验中具有通过增加外周血管阻力来升高血压的正常能力。NCA组在等长握力试验中心输出量未升高是一种异常反应，其原因有待研究。
