CBMN (UMR 5248), Univ. Bordeaux, CNRS, Bordeaux INP, 2 rue Robert Escarpit, 33600, Pessac, France.
Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780, Poznan, Poland.
Angew Chem Int Ed Engl. 2021 Aug 16;60(34):18461-18466. doi: 10.1002/anie.202104734. Epub 2021 Jul 1.
The very stable helices of 8-amino-2-quinolinecarboxylic acid oligoamides are shown to uptake Cu ions in their cavity through deprotonation of their amide functions with minimal alteration of their shape, unlike most metallo-organic structures which generally differ from their organic precursors. The outcome is the formation of intramolecular linear arrays of a defined number of Cu centers (up to sixteen in this study) at a 3 Å distance, forming a molecular mimic of a metal wire completely surrounded by an organic sheath. The helices pack in the solid state so that the arrays of Cu extend intermolecularly. Conductive-AFM and cyclic voltammetry suggest that electrons are transported throughout the metal-loaded helices in contrast with hole transport observed for analogous foldamers devoid of metal ions.
8-氨基-2-喹啉羧酸寡聚酰胺的非常稳定的螺旋结构被证明能够通过酰胺官能团的去质子化在其空腔中摄取 Cu 离子，而其形状几乎没有改变，这与大多数金属有机结构不同，大多数金属有机结构通常与其有机前体不同。其结果是在 3Å 的距离处形成了具有定义数量（在本研究中多达 16 个）Cu 中心的分子内线性阵列，形成了完全由有机鞘包围的金属线的分子模拟物。螺旋在固态中堆积，使得 Cu 阵列在分子间延伸。导电原子力显微镜和循环伏安法表明，电子在负载金属的螺旋中传输，与观察到的类似无金属离子的折叠体中的空穴传输形成对比。
