Livshits A V, Beliaev V I
Biull Eksp Biol Med. 1988 Jul;106(7):19-21.
Respiratory parameters have been studied by electrical stimulation of phrenic nerves (EPN) in 12 dogs. The optimal parameters of an electrical stimulus were found for long-term EPN. EPN increased minute respiratory volume, when respiratory rate raised to 18 per min, and decreased, when respiratory rate diminished to 6 per min. Another parameter--oxygen utilization index--diminished at high respiratory rate and increased at low one, which reflected hyper- or hypoventilation status, respectively. The data obtained indicate that controlled lung ventilation may maintain living status of dogs for a long time without alteration of general respiratory parameters.
通过电刺激12只狗的膈神经（EPN）对呼吸参数进行了研究。发现了用于长期膈神经电刺激的最佳电刺激参数。当呼吸频率提高到每分钟18次时，膈神经电刺激增加了每分通气量，而当呼吸频率降低到每分钟6次时则减少。另一个参数——氧利用指数——在高呼吸频率时降低，在低呼吸频率时增加，分别反映了通气过度或通气不足的状态。所获得的数据表明，受控的肺通气可以在不改变一般呼吸参数的情况下长期维持狗的生命状态。
