多模式镇痛对妇科癌症患者根治性切除术后的影响。
Effect of multimodal analgesia on gynecological cancer patients after radical resection.
作者信息
Dong Wenyue, An Bin, Wang Yi, Cui Xiaoyan, Gan Jianhui
机构信息
Department of Anesthesiology, Tangshan People's Hospital, North China University of Science and Technology Tangshan 063000, Hebei Province, China.
Department of Anesthesiology, Tangshan Maternity and Child Healthcare Hospital Tangshan 063000, Hebei Province, China.
出版信息
Am J Transl Res. 2021 Apr 15;13(4):2686-2693. eCollection 2021.
OBJECTIVE
This research was designed to probe into the effect of multimodal analgesia on gynecological cancer patients after radical resection.
METHODS
Ninety-eight cervical cancer patients undergoing laparoscopic radical resection in our hospital were included. Thereinto, 47 in the research group (RG) were given multimodal analgesia, and 51 in the control group (CG) were given conventional postoperative analgesia. The time of operation, anesthesia recovery room observation and extubation, postoperative NRS pain score, and the clinical manifestations of both groups were observed. The activity within three days after operation, the incidence of postoperative complications, hospitalization time and quality of life of both groups were compared.
RESULTS
The operation time of the RG was higher than that of the CG (P < 0.05), and the time of observation and extubation in the anesthesia room were lower than those in the CG (P < 0.05); the NRS pain score was lower than that of the CG (P < 0.05); the first time to get out of bed, and time of exhaust and diet were shorter than those of the CG (P < 0.05); the activity was better than that of the CG within three days after operation (P < 0.05); the incidence of complications was markedly lower than that in the CG (P < 0.05); the hospitalization time was shorter than that of the CG (P < 0.05); the postoperative quality of life was shorter than that in the CG (P < 0.05).
CONCLUSION
Multimodal analgesia is safe and effective for patients after laparoscopic radical resection of gynecological malignancies, which can speed up the recovery of diseases and improve the quality of life. Thus, it is worthy of clinical application.
目的
本研究旨在探讨多模式镇痛对妇科癌症患者根治性切除术后的影响。
方法
纳入我院98例行腹腔镜根治性切除术的宫颈癌患者。其中，研究组（RG）47例给予多模式镇痛，对照组（CG）51例给予传统术后镇痛。观察两组的手术时间、麻醉恢复室观察及拔管情况、术后NRS疼痛评分及临床表现。比较两组术后三天内的活动情况、术后并发症发生率、住院时间及生活质量。
结果
研究组手术时间高于对照组（P<0.05），麻醉恢复室观察及拔管时间低于对照组（P<0.05）；NRS疼痛评分低于对照组（P<0.05）；首次下床时间、排气及进食时间短于对照组（P<0.05）；术后三天内活动情况优于对照组（P<0.05）；并发症发生率明显低于对照组（P<0.05）；住院时间短于对照组（P<0.05）；术后生活质量优于对照组（P<0.05）。
结论
多模式镇痛对妇科恶性肿瘤腹腔镜根治性切除术后患者安全有效，可加速疾病恢复，提高生活质量，值得临床应用。
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