一种非哺乳类脊椎动物基底神经节系统中的钙结合蛋白：对凯门鳄的免疫组织化学研究

Calcium binding protein in the basal ganglia system of a non-mammalian vertebrate: an immunohistochemical study in the reptile Caiman crocodilus.

作者信息

Brauth S E, Kitt C A, Gerfen C R

机构信息

Department of Psychology, University of Maryland, College Park 20742.

出版信息

Brain Res. 1988 Jun 14;452(1-2):367-72. doi: 10.1016/0006-8993(88)90041-8.

DOI:10.1016/0006-8993(88)90041-8

PMID:3401743

Abstract

In Caiman, calbindin D28K immunoreactivity (CaBP) was observed within many neurons of the substantia nigra (SN) but only in the caudal portion of the area ventralis of Tsai (AVT). A dense CaBP fiber plexus showing some regional inhomogeneity was observed in the dorsolateral portion of the telencephalic ventrolateral area (VLA). These results are consistent with previous reports that the SN and AVT project to the dorsolateral and medial portions of the VLA, and strongly support the theory that the caiman VLA contains cell populations homologous to those found in the mammalian corpus striatum.

摘要

在凯门鳄中，在黑质（SN）的许多神经元内观察到钙结合蛋白D28K免疫反应性（CaBP），但仅在蔡氏腹侧区（AVT）的尾部区域观察到。在端脑腹外侧区（VLA）的背外侧部分观察到一个密集的CaBP纤维丛，显示出一些区域不均匀性。这些结果与之前关于SN和AVT投射到VLA的背外侧和内侧部分的报道一致，并有力地支持了凯门鳄VLA包含与哺乳动物纹状体中发现的细胞群同源的细胞群这一理论。