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印度南部一家三级护理医院收治的恙虫病患者的急性肾损伤和电解质异常

Acute kidney injury and electrolyte abnormalities in patients with scrub typhus admitted to a tertiary care hospital in southern India.

作者信息

Grover Raghav, Mehalingam Vadivelan

机构信息

Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

出版信息

J Family Med Prim Care. 2021 Jan;10(1):187-191. doi: 10.4103/jfmpc.jfmpc_1407_20. Epub 2021 Jan 30.

Abstract

INTRODUCTION

Scrub typhus is an acute febrile illness that is seen in many parts of India. Acute kidney injury (AKI) can occur in patients with scrub typhus who are not diagnosed and treated in the early stage of the disease. Such patients can have associated electrolyte abnormalities also.

OBJECTIVES

This study was done to find out the incidence of occurrence of AKI and electrolyte abnormalities among patients with scrub typhus and correlate the latter with the severity of AKI.

METHODS

This prospective, observational study included 38 patients with scrub typhus admitted to a tertiary care hospital in south India. Serum sodium and serum potassium levels of all the patients were measured at hospital admission. Also, serum creatinine levels of patients on all days of the hospital stay was measured along with other parameters like hemoglobin, leucocyte count, and platelet count.

RESULTS

The incidence of AKI among patients with scrub typhus was 13.16%. However, electrolyte abnormalities though seen in the patients did not correlate with AKI.

CONCLUSION

AKI is not an uncommon phenomenon in patients with scrub typhus. Electrolyte abnormalities in these patients did not correlate with the severity of AKI.

摘要

引言

恙虫病是一种在印度许多地区都可见的急性发热性疾病。在恙虫病患者中,如果在疾病早期未得到诊断和治疗,可能会发生急性肾损伤(AKI)。这类患者还可能伴有电解质异常。

目的

本研究旨在了解恙虫病患者中AKI和电解质异常的发生率,并将后者与AKI的严重程度相关联。

方法

这项前瞻性观察性研究纳入了38例入住印度南部一家三级护理医院的恙虫病患者。所有患者在入院时均测定血清钠和血清钾水平。此外,在患者住院期间的所有日子里,均测定血清肌酐水平以及其他参数,如血红蛋白、白细胞计数和血小板计数。

结果

恙虫病患者中AKI的发生率为13.16%。然而,尽管患者中可见电解质异常,但与AKI并无关联。

结论

AKI在恙虫病患者中并非罕见现象。这些患者的电解质异常与AKI的严重程度并无关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb19/8132768/d1a4f98a0875/JFMPC-10-187-g001.jpg

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