Department of Pulmonary Medicine, Sultan Abdulhamid Han Teaching Hospital, Istanbul, Turkey.
Interventional Pulmonology Unit, Istanbul, Turkey.
Niger J Clin Pract. 2021 May;24(5):633-639. doi: 10.4103/njcp.njcp_614_19.
: Postoperative bronchopleural fistula (BPF) remains a serious complication due to its high morbidity and mortality. Although various endoscopic techniques have been defined for the closure of BPF previously, no standard algorithm yet exists.
To study the effectiveness and safety of various endoscopic procedures in an interventional pulmonology unit.
The medical data of 15 postoperative BPF patients, who were undergone endoscopic intervention were retrospectively investigated.
The mean size of the fistulas determined by bronchoscopic evaluation was 7.93 ± 3.26 mm (range 3-15 mm). Applied procedures were as follows: stent implantation (n: 8, 53.3%), stent implantation and polidocanol application (n: 4, 26.7%), only Argon Plasma Coagulation (APC) application (n: 2,13.3%), polidocanol application (n: 1,6.7%). Complete fistula closure was achieved in three of the 15 patients (20%). The procedures were partly successful in five (33.3%) patients and failed to be successful in seven (46.6%) patients. Survival rates in regard to procedural success were determined and a statistically significant difference was found in five-year survival rates (P = 0.027, P < 0.05).
Our results demonstrated that bronchoscopic procedures can be safely and effectively performed in patients who were not eligible for surgery for various reasons.
由于其高发病率和死亡率,术后支气管胸膜瘘(BPF)仍然是一种严重的并发症。尽管以前已经定义了各种内镜技术来闭合 BPF,但尚未存在标准算法。
研究介入肺病学单位中各种内镜程序的有效性和安全性。
回顾性调查了 15 例接受内镜干预的术后 BPF 患者的医疗数据。
支气管镜评估确定的瘘口平均大小为 7.93 ± 3.26mm(范围 3-15mm)。应用的程序如下:支架植入(n:8,53.3%)、支架植入和聚多卡醇应用(n:4,26.7%)、仅氩等离子体凝固(APC)应用(n:2,13.3%)、聚多卡醇应用(n:1,6.7%)。15 例患者中有 3 例(20%)完全闭合瘘口。5 例(33.3%)患者的程序部分成功,7 例(46.6%)患者未能成功。确定了程序成功的生存率,五年生存率存在统计学显著差异(P=0.027,P<0.05)。
我们的结果表明,对于由于各种原因不适合手术的患者,支气管镜程序可以安全有效地进行。