Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY; and.
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD.
J Clin Neuromuscul Dis. 2021 Jun 1;22(4):183-191. doi: 10.1097/CND.0000000000000319.
We aimed to obtain nationally representative data on hospital readmission rates after Guillain-Barre syndrome (GBS).
International Classification of Disease, Ninth Revision codes from the 2013 National Readmissions Database identified adult GBS admissions, comorbidities, and readmission diagnoses. Logistic regression estimated odds ratios (ORs) for readmission.
Of 2109 GBS admissions identified, 20.8% were readmitted within 1 year and 12.2% within 30 days. Age did not predict readmission. Plasmapheresis use showed a nonsignificant trend toward readmission versus intravenous immunoglobulin use [OR 1.43, 95% confidence interval (CI) 1.00-2.051, P = 0.050]. Respiratory failure (OR 1.70, 95% CI 1.23-2.35, P = 0.0014), heart failure (OR 2.14, 95% CI 1.25-3.66, P = 0.0057), and renal failure (OR 2.00, 95% CI 1.20-3.32, P = 0.0078) predicted readmission. Top readmission diagnoses included GBS or chronic inflammatory demyelinating polyneuropathy (42.0%) and sepsis (3.5%).
One-fifth of GBS patients were readmitted within 1 year. Comorbid illnesses and respiratory complications increased a readmission risk but age did not.
我们旨在获得全国范围内吉兰-巴雷综合征（GBS）患者住院后再入院率的数据。
2013 年国家再入院数据库中的国际疾病分类，第九版代码确定了成人 GBS 入院、合并症和再入院诊断。逻辑回归估计了再入院的比值比（OR）。
在 2109 例 GBS 入院患者中，1 年内再入院率为 20.8%，30 天内再入院率为 12.2%。年龄与再入院无关。与静脉注射免疫球蛋白相比，血浆置换的使用显示出再入院的趋势，但无统计学意义[OR 1.43，95%置信区间（CI）1.00-2.051，P=0.050]。呼吸衰竭（OR 1.70，95%CI 1.23-2.35，P=0.0014）、心力衰竭（OR 2.14，95%CI 1.25-3.66，P=0.0057）和肾衰竭（OR 2.00，95%CI 1.20-3.32，P=0.0078）预测再入院。主要再入院诊断包括 GBS 或慢性炎症性脱髓鞘性多发性神经病（42.0%）和败血症（3.5%）。
五分之一的 GBS 患者在 1 年内再次入院。合并症和呼吸系统并发症增加了再入院风险，但年龄没有增加。
