维生素A对高山蝾螈再生芽基细胞影响的放射自显影评估
Autoradiographic evaluation of vitamin A effects on Triturus alpestris blastema cells.
作者信息
Koussoulakos S, Anton H J
机构信息
University of Athens, Zoological Laboratory, Greece.
出版信息
Cell Biol Int Rep. 1988 Apr;12(4):263-9. doi: 10.1016/0309-1651(88)90071-9.
Autoradiographic studies on Triturus alpestris regenerates treated with vitamin A palmitate for 4, 7, 11 and 14 days after amputation, reveal a considerable diminution in the percentage of cells duplicating DNA, as judged by measurements of labelling indices. Based on previous observations, that vitamin A promotes DNA-synthesis, mitosis and growth of regenerates, we conclude that the lower labelling indices calculated are due to an acceleration of S-phase processes, resulting in a concomitant reduction in its duration.
对蝾螈断肢后用棕榈酸视黄醇处理4天、7天、11天和14天的再生组织进行放射自显影研究，结果显示，根据标记指数测量判断，复制DNA的细胞百分比显著降低。基于之前维生素A促进再生组织DNA合成、有丝分裂和生长的观察结果，我们得出结论，计算得出的较低标记指数是由于S期进程加速，导致其持续时间相应缩短。
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