肿瘤“个性”检测指导治疗决策
A tumor "personality" test to guide therapeutic decision making.
机构信息
Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.
Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA; Department of Medicine (Oncology), Stanford University School of Medicine, Stanford, CA, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
出版信息
Cancer Cell. 2021 Jun 14;39(6):747-749. doi: 10.1016/j.ccell.2021.04.018. Epub 2021 May 20.
In this issue of Cancer Cell, Bagaev et al. discover conserved relationships between immune and stroma activity that are prognostic and predictive of response to immunotherapy across cancer types. The authors develop a visualization tool, akin to a tumor personality test, to integrate genomic and microenvironmental profiling and guide therapeutic decision-making.
在本期《癌细胞》中，Bagaev 等人发现了免疫和基质活性之间的保守关系，这些关系具有预后和预测作用，可以评估对跨癌症类型免疫治疗的反应。作者开发了一种可视化工具，类似于肿瘤个性测试，用于整合基因组和微环境分析，并指导治疗决策。
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