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分泌性中耳炎患者腺样体培养后纤毛活动降低的可逆性。

Reversibility of reduced ciliary activity on adenoids of patients with otitis media with effusion following culture.

作者信息

Ohashi Y, Nakai Y, Koshimo H, Ikeoka H, Esaki Y, Nakata J, Osako S

机构信息

Department of Otolaryngology, Osaka City University Medical School, Japan.

出版信息

Clin Otolaryngol Allied Sci. 1988 Jun;13(3):179-84. doi: 10.1111/j.1365-2273.1988.tb01114.x.

Abstract

We have studied the ciliary activity of the pharyngeal epithelium on adenoids obtained from patients with recurrent otitis media with effusion to assess indirectly the ciliary activity in the Eustachian tube. In conclusion, the following has been speculated from the present study: (1) middle ear effusions depress the ciliary activity; and (2) recovery of the reduced ciliary activity can be achieved in an effusion-free environment inasmuch as the ciliated cells have not undergone organic changes. Prompt elimination of the effusion, if present, is of critical importance for the recuperation of tubotympanic drainage, because a positive therapeutic effect resulting from elimination of the effusion can only be possible in early phase of the disease, before irreversible morphological lesions have occurred.

摘要

我们研究了从复发性分泌性中耳炎患者获取的腺样体咽上皮的纤毛活性,以间接评估咽鼓管的纤毛活性。总之,从本研究中推测出以下内容:(1)中耳积液会抑制纤毛活性;(2)由于纤毛细胞未发生器质性改变,在无积液环境中可实现降低的纤毛活性的恢复。如果存在积液,迅速消除积液对于咽鼓管鼓室引流的恢复至关重要,因为只有在疾病早期,在不可逆的形态学病变发生之前,消除积液才可能产生积极的治疗效果。

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