Berthout P, Cardot J C, Faivre R, Bernard Y, Baud M, Jouan A, Verdenet J, Bassand J P, Maurat J P, Bidet R
Service de Cardiologie, C.H.U. de Beançon, France.
Eur J Nucl Med. 1988;14(3):120-4. doi: 10.1007/BF00293534.
Left ventricular ejection fraction (LVEF) and regional wall motion abnormalities were determined in 40 patients (30 with coronary artery disease and 10 with valvular heart disease) using equilibrium radionuclide angiography. Scintigraphic acquisitions were collected in random order with 2 different collimators as follows: in anterior face (AF), left anterior oblique (25 degrees-45 degrees LAO) and 70 degrees LAO, with a vertical parallel hole collimator (VTC), and in 25 degrees-45 degrees LAO and 65 degrees-80 degrees LAO with a 30 degrees rotating slant hole collimator (RSHC), with the slant of the collimator directed towards the cardiac apex in both projections. Results were compared to contrast ventriculography (CV) performed in the 30 degrees right anterior view (3 segments: anterior, apical, inferior) and in a 60 degrees left anterior oblique view (3 segments: septal, apical and lateral). Radionuclide LVEF in both series was closely correlated with contrast ventriculographic LVEF (r = 0.89, VTC vs CV and r = 0.87, RSHC vs CV, respectively). Regional wall motion analysis was only performed among the 30 patients suffering from coronary heart disease. Eight contrast angiographic studies were normal and 22 abnormal. Global sensitivity and specificity were 100% and 63% with the VTC (3 false positives) and 91% and 87% with the 30 degrees RSHC (2 false negatives and 1 false positive, P = ns). Agreement for the localisation of the regional wall motion abnormalities between CV and radionuclide angiography was 70.6% with the VTC and 71.2% with the RSHC (P = ns).(ABSTRACT TRUNCATED AT 250 WORDS)
采用平衡放射性核素血管造影术对40例患者（30例冠心病患者和10例瓣膜性心脏病患者）的左心室射血分数（LVEF）和局部室壁运动异常进行测定。使用2种不同准直器以随机顺序采集闪烁扫描图像如下：在前位（AF）、左前斜位（25度 - 45度LAO）和70度LAO，使用垂直平行孔准直器（VTC）；在25度 - 45度LAO和65度 - 80度LAO，使用30度旋转斜孔准直器（RSHC），在两个投照位中准直器的倾斜方向均朝向心尖。将结果与在右前30度视图（3个节段：前壁、心尖、下壁）和左前斜60度视图（3个节段：间隔、心尖和侧壁）进行的对比心室造影（CV）结果相比较。两个系列中的放射性核素LVEF与对比心室造影LVEF均密切相关（分别为r = 0.89，VTC与CV对比；r = 0.87，RSHC与CV对比）。仅对30例冠心病患者进行了局部室壁运动分析。8例对比血管造影研究结果正常，22例异常。VTC的总体敏感性和特异性分别为100%和63%（3例假阳性），30度RSHC的总体敏感性和特异性分别为91%和87%（2例假阴性和1例假阳性，P = 无显著差异）。CV与放射性核素血管造影之间局部室壁运动异常定位的一致性，VTC为70.6%，RSHC为71.2%（P = 无显著差异）。（摘要截取自250字）
