99mTc标记的单克隆抗体225.28S的（Fab'）2片段被良性眼部痣摄取。
Uptake of 99mTc labelled (Fab')2 fragments of monoclonal antibody 225.28S by a benign ocular naevus.
作者信息
Bomanji J, Hungerford J L, Granowska M, Britton K E
机构信息
Department of Nuclear Medicine, St Bartholomew's Hospital, London, UK.
出版信息
Eur J Nucl Med. 1988;14(3):165-6. doi: 10.1007/BF00293543.
PMID:3402506
Abstract
Malignant melanoma is one of the most common primary intraocular neoplasms. Recently, 99mTc radiolabelled (Fab')2 fragments of monoclonal antibody 225.28S raised against cutaneous melanomas have been used for imaging uveal melanomas. We report here a case where uptake of radiolabelled antibody was observed in a choroidal melanoma of the right eye and a benign choroidal naevus of the left.
摘要
恶性黑色素瘤是最常见的原发性眼内肿瘤之一。最近，针对皮肤黑色素瘤产生的单克隆抗体225.28S的99mTc放射性标记（Fab'）2片段已被用于葡萄膜黑色素瘤的成像。我们在此报告一例，在右眼脉络膜黑色素瘤和左眼良性脉络膜痣中观察到放射性标记抗体的摄取。
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