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32P试验在脉络膜恶性黑色素瘤治疗中的应用:一项五年随访研究。

The use of the 32P test in the management of malignant melanoma of the choroid: a five-year follow-up study.

作者信息

Hagler W S, Jarrett W H, Killian J H

出版信息

Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1977 Jan-Feb;83(1):49-60.

PMID:898475
Abstract

We have presented mortality, clinical, and histopathologic data on a consecutive group of patients with malignant choroidal melanoma studied by a radioactive phosphorus uptake test. The mortality of 14% is the lowest reported in the literature (Table 11) and suggests that early diagnosis followed by prompt enucleation affords the patient a favorable prognosis. There is no evidence to suggest that the surgical manipulations involved expose the patient to added risks. Factors of importance regarding prognosis of malignant melanoma include tumor size, cell type, and presence or absence of extrascleral extension. Of these, we believe that cell type is the most important factor. Our data to date do not permit us to predict from the 32P tests the prognosis for patient survival.

摘要

我们已经展示了一组通过放射性磷摄取试验研究的连续性脉络膜恶性黑色素瘤患者的死亡率、临床及组织病理学数据。14%的死亡率是文献报道中最低的(表11),这表明早期诊断后迅速眼球摘除术可为患者带来良好预后。没有证据表明所涉及的手术操作会给患者带来额外风险。关于恶性黑色素瘤预后的重要因素包括肿瘤大小、细胞类型以及是否存在巩膜外扩展。其中,我们认为细胞类型是最重要的因素。我们目前的数据不允许我们根据32P试验预测患者生存预后。

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