Getting Excited Through Cyclin: A Role for Endothelial Cdk5 Signaling in Hippocampal Hyperexcitability.
作者信息
Aroor Alisha, Brewster Amy L
出版信息
Epilepsy Curr. 2020 Oct 12;20(6):396-398. doi: 10.1177/1535759720958418. eCollection 2020 Nov-Dec.
Abstract
摘要
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本文引用的文献
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Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis.内皮细胞 Cdk5 缺失通过 CXCL1/CXCR2 介导的反应性星形胶质细胞增生导致自发性癫痫的发生。
J Exp Med. 2020 Jan 6;217(1). doi: 10.1084/jem.20180992.
2
CDK5: Key Regulator of Apoptosis and Cell Survival.细胞周期蛋白依赖性激酶5：细胞凋亡与细胞存活的关键调节因子
Biomedicines. 2019 Nov 6;7(4):88. doi: 10.3390/biomedicines7040088.
3
Synaptic roles of cyclin-dependent kinase 5 & its implications in epilepsy.细胞周期蛋白依赖性激酶5的突触作用及其在癫痫中的意义。
Indian J Med Res. 2017 Feb;145(2):179-188. doi: 10.4103/ijmr.IJMR_1249_14.
4
Cyclin-dependent kinases.细胞周期蛋白依赖性激酶
Genome Biol. 2014;15(6):122. doi: 10.1186/gb4184.
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Ceftriaxone treatment after traumatic brain injury restores expression of the glutamate transporter, GLT-1, reduces regional gliosis, and reduces post-traumatic seizures in the rat.颅脑损伤后使用头孢曲松治疗可恢复谷氨酸转运体 GLT-1 的表达，减少区域性神经胶质增生，并减少大鼠的外伤性癫痫发作。
J Neurotrauma. 2013 Aug 15;30(16):1434-41. doi: 10.1089/neu.2012.2712. Epub 2013 Jul 25.
6
Cerebrovascular remodeling and epilepsy.脑血管重构与癫痫。
Neuroscientist. 2013 Jun;19(3):304-12. doi: 10.1177/1073858412462747. Epub 2012 Oct 16.
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Blood-brain barrier dysfunction and epilepsy: pathophysiologic role and therapeutic approaches.血脑屏障功能障碍与癫痫：病理生理作用与治疗方法。
Epilepsia. 2012 Nov;53(11):1877-86. doi: 10.1111/j.1528-1167.2012.03637.x. Epub 2012 Aug 20.
8
Involvement of cyclin-dependent kinase-5 in the kainic acid-mediated degeneration of glutamatergic synapses in the rat hippocampus.周期素依赖性激酶-5 参与了海人酸诱导的大鼠海马谷氨酸能突触的变性。
Eur J Neurosci. 2011 Oct;34(8):1212-21. doi: 10.1111/j.1460-9568.2011.07858.x. Epub 2011 Oct 7.
9
Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.细胞周期蛋白依赖性激酶5对海马体及行为兴奋性的调节作用
PLoS One. 2009 Jun 4;4(6):e5808. doi: 10.1371/journal.pone.0005808.
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