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伊伐布雷定对癌症治疗相关心脏功能障碍所致失代偿性心力衰竭的影响。

Impact of ivabradine in decompensated heart failure due to cancer therapy-related cardiac dysfunction.

作者信息

Nakano Yusuke, Ando Hirohiko, Suzuki Wataru, Ohashi Hirofumi, Suzuki Yasushi, Takashima Hiroaki, Amano Tetsuya

机构信息

Department of Cardiology Aichi Medical University Nagakute Japan.

出版信息

Clin Case Rep. 2021 May 5;9(5):e04133. doi: 10.1002/ccr3.4133. eCollection 2021 May.

DOI:10.1002/ccr3.4133
PMID:34026170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8136441/
Abstract

In cases of decompensated heart failure related to cancer therapy-related cardiac dysfunction, ivabradine administration could lead to an increased stroke volume by reducing the sinus heart rate, resulting in favorable hemodynamics. Assessment of the overlap between the E- and A-waves facilitates understanding the effects of ivabradine in such cases.

摘要

在与癌症治疗相关的心脏功能障碍所致失代偿性心力衰竭病例中,使用伊伐布雷定可通过降低窦性心率来增加每搏输出量,从而产生有利的血流动力学效果。评估E波和A波之间的重叠情况有助于了解伊伐布雷定在此类病例中的作用。

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Prevention and Treatment of Chemotherapy-Induced Cardiotoxicity.化疗所致心脏毒性的防治
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Increased sarcoplasmic/endoplasmic reticulum calcium ATPase 2a activity underlies the mechanism of the positive inotropic effect of ivabradine.
伊伐布雷定预防女性原发性乳腺癌患者蒽环类药物诱导的心脏毒性:一项前瞻性、随机、开放标签临床试验。
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Effects of ivabradine on the prevention of intradialytic hypotension in a dialytic patient with heart failure with reduced ejection fraction.依伐布雷定对射血分数降低的心力衰竭透析患者预防透析中低血压的影响。
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Ivabradine for Chemotherapy-Related Cardiac Dysfunction in Breast Cancer.
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伊伐布雷定正性变力作用的机制在于肌浆/内质网钙 ATP 酶 2a 活性增加。
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Initiation of ivabradine in cardiogenic shock.在心原性休克中启动伊伐布雷定。
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2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America.2017年美国心脏病学会/美国心脏协会/美国心力衰竭学会对2013年美国心脏病学基金会/美国心脏协会心力衰竭管理指南的重点更新:美国心脏病学会/美国心脏协会临床实践指南工作组及美国心力衰竭学会的报告
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