Pham Duyen N K, Chadeayne Andrew R, Golen James A, Manke David R
University of Massachusetts Dartmouth, 285 Old Westport Road, North Dartmouth, MA 02747, USA.
CaaMTech, LLC, 58 East Sunset Way, Suite 209, Issaquah, WA 98027, USA.
Acta Crystallogr E Crystallogr Commun. 2021 Apr 13;77(Pt 5):522-526. doi: 10.1107/S2056989021003753. eCollection 2021 May 1.
The solid-state structures of the synthetic psychedelic 5-meth-oxy-,-di--propyl-tryptamine (5-MeO-DPT) {systematic name: -[2-(5-meth-oxy-1-indol-3-yl)eth-yl]--propyl-propan-1-amine}, CHNO, and its fumarate salt, bis-(5-meth-oxy-,-di--propyl-tryptammonium) fumarate (systematic name: bis-{-[2-(5-meth-oxy-1-indol-3-yl)eth-yl]--propyl-propan-1-aminium} but-2-ene-dio-ate), 2CHNO·CHO , are reported. The freebase has a single tryptamine mol-ecule in the asymmetric unit. The mol-ecules are linked together by N-H⋯N hydrogen bonds in zigzag chains along the [010] direction. The fumarate salt has a single tryptammonium cation and half of a fumarate dianion in the asymmetric unit. The tryptammonium and fumarate ions are held together in one-dimensional chains by a series of N-H⋯O hydrogen bonds. These chains are combinations of (22) rings, and (14) and (28) parallel chains along [001].
报道了合成致幻剂5-甲氧基-N,N-二异丙基色胺（5-MeO-DPT）{系统名称：N-[2-(5-甲氧基-1-吲哚-3-基)乙基]-N-异丙基丙-1-胺}，化学式为C₁₃H₂₂N₂O，及其富马酸盐，双-(5-甲氧基-N,N-二异丙基色胺铵)富马酸盐（系统名称：双-{N-[2-(5-甲氧基-1-吲哚-3-基)乙基]-N-异丙基丙-1-铵}丁-2-烯二酸酯），化学式为2C₁₃H₂₂N₂O·C₄H₄O₄。游离碱在不对称单元中有单个色胺分子。分子通过N-H⋯N氢键沿[010]方向以锯齿链相连。富马酸盐在不对称单元中有单个色胺铵阳离子和半个富马酸二阴离子。色胺铵离子和富马酸离子通过一系列N-H⋯O氢键在一维链中结合在一起。这些链是(22)环以及沿[001]方向的(14)和(28)平行链的组合。
