Trull Brent, Zhang Zach, Boyd Kirsty, Allen Murray, Zhang Jing
Division of Plastic Surgery, Department of Surgery, University of Ottawa, Ontario, Canada.
Division of Plastic Surgery, Department of Surgery, University of British Columbia, Vancouver, Canada.
Plast Surg (Oakv). 2021 May;29(2):122-127. doi: 10.1177/2292550320954093. Epub 2020 Oct 14.
Microsurgical free tissue transfer for lower limb reconstruction presents unique challenges in the postoperative period where dependency promotes interstitial fluid diffusion and reduced tissue perfusion. Management of flap edema, venous congestion, and ischaemic conditioning is critical for flap survival. Little evidence exists to guide postoperative protocols in the initiation and progression of lower extremity dangle, monitoring, and anticoagulation. We aim to describe current trends for postoperative dependency protocols by surveying Canadian microsurgeons.
Plastic surgeons performing lower limb microvascular reconstruction at Fellow of The Royal College of Surgeons of Canada approved teaching institutions were administered a 17-question anonymous electronic survey. A literature review was conducted to identify protocols and consensus opinions in other jurisdictions.
All respondents (n = 16) monitored flaps clinically, with conventional Doppler used by 13 respondents. Anticoagulation was employed by 15 of 16 respondents, and 9 of 16 used 2 or more agents. The most common agents were aspirin, followed by low-molecular-weight heparin. Significant variability existed in dangling protocols. Dependency was initiated at postoperative day (POD) 3 to 10 (mean POD: 6 ± 1.64 standard deviation), with intervals ranging from 5 to 20 minutes and frequencies ranging from 1 to 6 times per day. Nearly half allowed both increasing duration and frequency of dependency. Flap success rates were above 90%, and the median length of stay was 10 to 12 days.
While flap success rates across the country are similar, no consensus exists for postoperative dependency protocols amongst Canadian microsurgeons. Prospective randomised controlled trials are warranted to evaluate early aggressive dependency protocols to reduce length of stay and cost.
用于下肢重建的显微外科游离组织移植在术后阶段面临独特挑战,因为肢体下垂会促进组织间液扩散并降低组织灌注。皮瓣水肿、静脉淤血和缺血预处理的管理对皮瓣存活至关重要。目前几乎没有证据可指导下肢下垂起始、进展、监测及抗凝方面的术后方案。我们旨在通过对加拿大显微外科医生进行调查来描述术后下垂方案的当前趋势。
在加拿大皇家外科医师学院认可的教学机构中进行下肢微血管重建的整形外科医生接受了一项包含17个问题的匿名电子调查。进行文献综述以确定其他司法管辖区的方案和共识意见。
所有受访者(n = 16)均对皮瓣进行临床监测,13名受访者使用传统多普勒。16名受访者中有15名采用了抗凝措施,16名中有9名使用了2种或更多药物。最常用的药物是阿司匹林,其次是低分子肝素。下垂方案存在显著差异。下垂起始于术后第3至10天(平均术后天数:6±1.64标准差),每次间隔5至20分钟,每天频率为1至6次。近一半的受访者允许增加下垂持续时间和频率。皮瓣成功率高于90%,中位住院时间为10至12天。
虽然全国皮瓣成功率相似,但加拿大显微外科医生在术后下垂方案上未达成共识。有必要进行前瞻性随机对照试验,以评估早期积极的下垂方案,以缩短住院时间和降低成本。