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铟催化的 C-F 键转化通过氧化金属化/β-氟消除来构建氟化异香豆素。

Indium-Catalyzed C-F Bond Transformation through Oxymetalation/β-Fluorine Elimination to Access Fluorinated Isocoumarins.

机构信息

Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Innovative Catalysis Science Division, Institute for Open and Transdisciplinary Research Initiatives (ICS-OTRI), Osaka University, Suita, Osaka, 565-0871, Japan.

出版信息

Chemistry. 2021 Jun 4;27(32):8232. doi: 10.1002/chem.202101570. Epub 2021 May 24.

DOI:10.1002/chem.202101570
PMID:34028103
Abstract

Invited for the cover of this issue are Yoshihiro Nishimoto, Makoto Yasuda and co-workers at Osaka University and MOLSIS Inc.. The image depicts the crafting of a gladiator's shield to represent the reaction reported in this work. Read the full text of the article at 10.1002/chem.202100672.

摘要

本期特邀封面人物是来自大阪大学的西本佳广(Yoshihiro Nishimoto)、安田诚(Makoto Yasuda)及其同事,以及 MOLSIS 公司。本期封面图片描绘了一个制作角斗士盾牌的过程,以代表本期工作中所报道的反应。全文请阅读 10.1002/chem.202100672。

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引用本文的文献

1
Isocoumarins: a new class of selective carbonic anhydrase IX and XII inhibitors.异香豆素:一类新型的碳酸酐酶 IX 和 XII 抑制剂。
J Enzyme Inhib Med Chem. 2022 Dec;37(1):743-748. doi: 10.1080/14756366.2022.2041630.