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急性粘连性小肠梗阻保守治疗的新方法

[New approaches in conservative treatment of acute adhesive small bowel obstruction].

作者信息

Larichev S E, Shapovalyants S G, Zavyalov B G, Shabrin A V, Omelyanovich D A, Zheleshchikov A L

机构信息

City Clinical Hospital No. 17, Moscow, Russia.

Pirogov Russian National Research Medical University, Moscow, Russia.

出版信息

Khirurgiia (Mosk). 2021(6):45-53. doi: 10.17116/hirurgia202106145.

DOI:10.17116/hirurgia202106145
PMID:34029035
Abstract

OBJECTIVE

To improve the outcomes of therapy of acute adhesive small bowel obstruction via development of a comprehensive management including CT, deep endoscopy-assisted nasointestinal drainage of small bowel with injection of a water-soluble contrast.

MATERIAL AND METHODS

There were 128 patients with acute adhesive small bowel obstruction for the period from 2015 to 2018. The study included 2 groups of patients depending on therapeutic approach and duration of treatment. In the first group, conventional approach for acute adhesive small bowel obstruction was applied. Upon admission, all patients with confirmed acute adhesive small bowel obstruction underwent gastric intubation for decompression of the upper gastrointestinal tract. Barium sulfate injection followed by X-ray examination was performed to assess an effectiveness of therapy. In the second group, computed tomography was performed in addition to X-ray examination and ultrasound. Moreover, conservative treatment included deep endoscopy-assisted nasointestinal drainage and subsequent administration of a water-soluble contrast in addition to traditional approaches.

RESULTS

Therapy was effective in 99 (71.2%) patients; 39 (28.8%) ones required surgery. Deep endoscopy-assisted nasointestinal drainage with injection of a water-soluble contrast was effective in 45 (78.9%) patients. Overall mortality in traditional approach was 1.4%, postoperative mortality - 3.7%. There were no lethal outcomes in case of a new approach.

CONCLUSION

Deep endoscopy-assisted nasointestinal drainage with injection of a water-soluble contrast is the most effective therapeutic method for acute adhesive small bowel obstruction (78.9%). These findings can significantly improve treatment outcomes in these patients.

摘要

目的

通过制定包括CT、深部内镜辅助小肠鼻肠引流并注入水溶性造影剂在内的综合管理方案,改善急性粘连性小肠梗阻的治疗效果。

材料与方法

2015年至2018年期间有128例急性粘连性小肠梗阻患者。根据治疗方法和治疗持续时间,该研究包括两组患者。第一组采用急性粘连性小肠梗阻的传统治疗方法。入院时,所有确诊为急性粘连性小肠梗阻的患者均接受胃插管以进行上消化道减压。进行硫酸钡注射并随后进行X线检查以评估治疗效果。第二组除了进行X线检查和超声检查外,还进行了计算机断层扫描。此外,保守治疗除了传统方法外,还包括深部内镜辅助小肠鼻肠引流及随后注入水溶性造影剂。

结果

99例(71.2%)患者治疗有效;39例(28.8%)患者需要手术治疗。深部内镜辅助小肠鼻肠引流并注入水溶性造影剂在45例(78.9%)患者中有效。传统方法的总死亡率为1.4%,术后死亡率为3.7%。新方法无致死病例。

结论

深部内镜辅助小肠鼻肠引流并注入水溶性造影剂是治疗急性粘连性小肠梗阻最有效的治疗方法(78.9%)。这些发现可显著改善这些患者的治疗效果。

相似文献

1
[New approaches in conservative treatment of acute adhesive small bowel obstruction].急性粘连性小肠梗阻保守治疗的新方法
Khirurgiia (Mosk). 2021(6):45-53. doi: 10.17116/hirurgia202106145.
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Therapeutic value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: a prospective randomized trial.泛影葡胺在保守治疗失败后的粘连性小肠梗阻中的治疗价值:一项前瞻性随机试验
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Oral water soluble contrast for the management of adhesive small bowel obstruction.口服水溶性造影剂用于粘连性小肠梗阻的治疗
Cochrane Database Syst Rev. 2005 Jan 25(1):CD004651. doi: 10.1002/14651858.CD004651.pub2.
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Oral water soluble contrast for the management of adhesive small bowel obstruction.口服水溶性造影剂用于粘连性小肠梗阻的治疗
Cochrane Database Syst Rev. 2007 Jul 18;2007(3):CD004651. doi: 10.1002/14651858.CD004651.pub3.
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Value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: a prospective evaluation.泛影葡胺在保守治疗失败后的粘连性小肠梗阻中的价值:一项前瞻性评估。
World J Gastroenterol. 2005 Jun 28;11(24):3742-5. doi: 10.3748/wjg.v11.i24.3742.
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[Nasointestinal intubation in the treatment of acute adhesive small bowel obstruction].
Khirurgiia (Mosk). 2022(12. Vyp. 2):81-89. doi: 10.17116/hirurgia202212281.
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Evaluation of a water-soluble contrast protocol for nonoperative management of pediatric adhesive small bowel obstruction.水溶性造影剂方案用于小儿粘连性小肠梗阻非手术治疗的评估
J Pediatr Surg. 2019 Jan;54(1):184-188. doi: 10.1016/j.jpedsurg.2018.10.002. Epub 2018 Oct 5.
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Timing of surgery, intestinal ischemia and other real factors of mortality in acute adhesive small bowel obstruction: a multiple-center study.手术时机、肠缺血和其他急性黏连性小肠梗阻死亡的实际因素:一项多中心研究。
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Water-soluble contrast agent in adhesive small bowel obstruction: a systematic review and meta-analysis of diagnostic and therapeutic value.水溶性造影剂在粘连性小肠梗阻中的应用:诊断和治疗价值的系统评价与Meta分析
Am J Surg. 2016 Jun;211(6):1114-25. doi: 10.1016/j.amjsurg.2015.06.012. Epub 2015 Aug 12.

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