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用罗沙前列醇对胃炎患者进行短期和长期治疗。

Short- and long-term treatment with rosaprostol of patients with gastritis.

作者信息

Di Simone A, Riegler G, Esposito P, Ciani D

机构信息

Department of Medical Pathology, I School of Medicine and Surgery, University of Naples, Italy.

出版信息

Int J Clin Pharmacol Res. 1988;8(3):217-21.

PMID:3403108
Abstract

Therapy with rosaprostol was applied in 25 patients with gastritis, namely 11 cases for about 30 days and 14 for 60 days, without further gastro-protective treatments. The drug induced an early complete disappearance of subjective and objective symptoms, already at the end of the first ten days of treatment, whereas the endoscopic and the histological findings revealed a highly significant improvement at the end of the treatment, with normalization in nearly all the cases. The drug was well tolerated, and did not induce diarrhoea nor change haemodynamic parameters. These highly significant results emphasize the efficacy and safety of the drug.

摘要

对25例胃炎患者应用罗沙前列醇进行治疗,其中11例治疗约30天,14例治疗60天,未采取进一步的胃保护治疗。该药在治疗开始后的前十天末就能使主观和客观症状早期完全消失,而在内镜检查和组织学检查结果显示,在治疗结束时病情有高度显著改善,几乎所有病例均恢复正常。该药耐受性良好,未引起腹泻,也未改变血流动力学参数。这些高度显著的结果强调了该药的有效性和安全性。

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