Department of Psychiatry/Island Medical Program, University of British Columbia, Victoria, Canada.
Corresponding author: Nichole Fairbrother, PhD, Room 002, Pearkes Bldg, Queen Alexandra Centre for Children's Health, 2400 Arbutus Rd, Victoria, BC V8N 1V7, Canada (
J Clin Psychiatry. 2021 Mar 23;82(2):20m13398. doi: 10.4088/JCP.20m13398.
During the perinatal period, women are at an increased risk for the onset/exacerbation of obsessive-compulsive disorder (OCD) and may experience perinatal-specific obsessions and/or compulsions. Past research has provided preliminary findings regarding the prevalence of OCD in the perinatal period but has often reported limited metrics and ignored perinatal specific symptoms. This research aimed to assess the prevalence and incidence of maternal OCD between the third trimester in pregnancy and 6 months postpartum. An unselected sample of 763 English-speaking pregnant women and new mothers participated in a longitudinal, province-wide study between their third trimester in pregnancy and 9 months postpartum. They completed 3 online questionnaires and interviews (data collected between February 9, 2014, and February 14, 2017) and were administered a diagnostic interview to determine OCD status based on diagnostic criteria. A weighted prenatal period prevalence of 7.8% and a postpartum period prevalence of 16.9% were found. The average, prenatal, point prevalence estimate was 2.9%, and the average, postpartum, point prevalence estimate was 7.0%. Point prevalence gradually increased over the course of pregnancy and the early postpartum, attaining a peak of close to 9% at approximately 8 weeks postpartum, with a gradual decline thereafter. The cumulative incidence of new OCD diagnoses was estimated at 9% by 6 months postpartum. Our study suggests that when women are encouraged to report their perinatal-specific symptoms, and current diagnostic criteria are applied, estimates for perinatal OCD may be higher than previously believed.
在围产期,女性罹患强迫症(OCD)的风险增加,并且可能经历围产期特有的强迫观念和/或强迫行为。既往研究提供了围产期 OCD 的患病率的初步结果,但往往报告的指标有限,忽略了围产期特有的症状。本研究旨在评估妊娠晚期至产后 6 个月期间母亲 OCD 的患病率和发病率。
一个未选择的 763 名英语母语的孕妇和新妈妈的样本参与了一项纵向、全省范围的研究,研究时间从妊娠晚期至产后 9 个月。她们完成了 3 次在线问卷和访谈(数据收集于 2014 年 2 月 9 日至 2017 年 2 月 14 日),并接受了诊断访谈,根据诊断标准确定 OCD 状况。
研究发现,产前患病率为 7.8%,产后患病率为 16.9%。平均产前时点患病率估计值为 2.9%,平均产后时点患病率估计值为 7.0%。点患病率在整个妊娠和产后早期逐渐增加,在产后约 8 周时达到接近 9%的峰值,此后逐渐下降。到产后 6 个月时,新发 OCD 诊断的累积发病率估计为 9%。
我们的研究表明,当鼓励女性报告其围产期特有的症状并应用当前的诊断标准时,围产期 OCD 的估计患病率可能高于先前认为的水平。