Dixon D, Reinhard G R, Kazacos K R, Arriaga C
Laboratory Animal Research Center, Rockefeller University, New York, NY 10021.
J Am Vet Med Assoc. 1988 Jul 15;193(2):251-3.
Baylisascaris spp larvae were determined to cause CNS disease in 3 prairie dogs maintained at a research facility. Clinical signs consisted of ataxia, stumbling, and head tilt, which progressed to severe torticollis, paddling in lateral recumbency, and loss of the righting reflex. Gross lesions were not found at necropsy. Microscopically, the cerebellar white matter and medulla oblongata were most severely affected and had numerous sections of large ascarid larvae. Our findings indicated that natural infections of Baylisacaris spp larvae can cause CNS disease in prairie dogs. Also, Baylisascaris spp larval infection should be considered in differential diagnoses of CNS disease in prairie dogs.
已确定拜氏蛔线虫属幼虫在一家研究机构饲养的3只草原犬鼠中引发了中枢神经系统疾病。临床症状包括共济失调、蹒跚和头部倾斜，进而发展为严重的斜颈、侧卧划水以及翻正反射丧失。尸检未发现肉眼可见的病变。显微镜下，小脑白质和延髓受影响最为严重，有大量大型蛔虫幼虫切片。我们的研究结果表明，拜氏蛔线虫属幼虫的自然感染可在草原犬鼠中引发中枢神经系统疾病。此外，在草原犬鼠中枢神经系统疾病的鉴别诊断中应考虑拜氏蛔线虫属幼虫感染。
