Center for Microbiology, VIB, Leuven 3001, Belgium; Centre of Microbial and Plant Genetics, KU Leuven, Leuven 3001, Belgium.
Center for Microbiology, VIB, Leuven 3001, Belgium; Centre of Microbial and Plant Genetics, KU Leuven, Leuven 3001, Belgium.
Curr Biol. 2021 May 24;31(10):R493-R495. doi: 10.1016/j.cub.2021.03.072.
In a new paper in this issue, Murawski and Brynildsen define chromosomal ploidy as an important characteristic for persistence following fluoroquinolone treatment. Bacteria carrying two chromosomes are more likely to repair DNA damage through homologous recombination compared with cells containing a single chromosome.
在本期的一篇新论文中，Murawski 和 Brynildsen 将染色体倍性定义为氟喹诺酮类药物治疗后持续存在的一个重要特征。与含有单个染色体的细胞相比，携带两条染色体的细菌更有可能通过同源重组修复 DNA 损伤。
