Sakurada Hiroki, Koyasu Sho, Sugimoto Akihiko, Nakanishi Etsuro, Nakamoto Yuji
From the Departments of Diagnostic Imaging and Nuclear Medicine.
Diagnostic Pathology.
Clin Nucl Med. 2021 Oct 1;46(10):850-852. doi: 10.1097/RLU.0000000000003737.
A 77-year-old man with parkinsonism was referred to the department of neurology for further examination. Cardiac 123I-MIBG scintigraphy unexpectedly showed strong uptake in the left shoulder, suggestive of MIBG-avid tumors including paraganglioma. MRI revealed multiple nodules suggestive of lymphoma. A biopsy was performed, which led to the pathological diagnosis of diffuse large B-cell lymphoma. Cardiac MIBG scintigraphy sometimes shows unexpected findings outside the mediastinum. In addition, lymphoma should also be added to the list of differential diagnoses for MIBG-positive tumors.
一名患有帕金森症的77岁男性被转诊至神经科进行进一步检查。心脏碘-123间碘苄胍（123I-MIBG）闪烁扫描意外显示左肩有强烈摄取，提示存在MIBG亲和性肿瘤，包括副神经节瘤。磁共振成像（MRI）显示多个结节，提示为淋巴瘤。进行了活检，病理诊断为弥漫性大B细胞淋巴瘤。心脏MIBG闪烁扫描有时会在纵隔外显示意外发现。此外，淋巴瘤也应列入MIBG阳性肿瘤的鉴别诊断清单中。
