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婚姻状况与日本认知功能的关系:来自富山痴呆症调查的结果。

Association between marital status and cognitive function in Japan: results from the Toyama Dementia Survey.

机构信息

Faculty of Nursing Science, Tsuruga Nursing University, Tsuruga, Japan.

Department of Epidemiology and Health Policy, School of Medicine, University of Toyama, Toyama, Japan.

出版信息

Psychogeriatrics. 2021 Jul;21(4):627-635. doi: 10.1111/psyg.12724. Epub 2021 May 25.

Abstract

BACKGROUND

This study aims to clarify the association between marital status and dementia in Japan, adjusting for socioeconomic, lifestyle, and lifestyle-related disease factors.

METHODS

Data from the Japanese Toyama Dementia Survey were used. Individuals aged ≥65 years living in Toyama Prefecture were randomly selected, and 1171 participants were analysed, with a sampling rate of 0.5%. The participants' marital status, socioeconomic status, lifestyle factors, and lifestyle-related diseases were assessed. The odds ratio (OR) of marital status for each lifestyle factor and medical histories were calculated by logistic regression analysis. The OR of marital status for dementia was also calculated by logistic regression analysis.

RESULTS

The prevalence of dementia was 7.4% for married, and 20.6% for non-married participants. Non-married participants showed a higher prevalence of a history of stroke than married participants. The age- and sex-adjusted OR of marital status for dementia was 1.99 (95% confidence interval (CI) 1.24-3.18) for non-married compared with married participants. Following variable adjustments, the OR for dementia was higher for non-married participants (adjusted OR 1.71; 95% CI 1.03-2.85).

CONCLUSIONS

Non-marital status was an independent risk factor for dementia in Japan even after adjusting for socioeconomic, lifestyle, and lifestyle-related disease factors. Non-married people were more likely to have dementia because of their history of stroke.

摘要

背景

本研究旨在明确日本的婚姻状况与痴呆之间的关联,同时调整了社会经济地位、生活方式和生活方式相关疾病等因素。

方法

本研究使用了日本富山痴呆症调查的数据。从富山县随机选择了年龄≥65 岁的居民,共 1171 名参与者参与了研究,抽样率为 0.5%。评估了参与者的婚姻状况、社会经济地位、生活方式因素和生活方式相关疾病。通过逻辑回归分析计算了婚姻状况对每种生活方式因素和病史的比值比(OR)。同时,也通过逻辑回归分析计算了婚姻状况对痴呆的比值比(OR)。

结果

已婚参与者的痴呆患病率为 7.4%,而非已婚参与者的痴呆患病率为 20.6%。与已婚参与者相比,非已婚参与者有更高的卒中病史。在调整年龄和性别后,非已婚参与者的痴呆患病风险比已婚参与者高 1.99 倍(95%置信区间 1.24-3.18)。在调整了社会经济地位、生活方式和生活方式相关疾病等因素后,非已婚参与者的痴呆患病风险比仍然更高(调整后的 OR 为 1.71;95%置信区间 1.03-2.85)。

结论

即使在调整了社会经济地位、生活方式和生活方式相关疾病等因素后,非婚姻状况仍然是非日本痴呆的独立危险因素。非已婚人群更易患痴呆,可能是由于他们的卒中病史。

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