Wen Y, Yu L Z, Du L B, Wei D H, Liu Y Y, Yang Z Y, Zheng Y D, Wu Z, Yu X Y, Zhao L, Yu Y W, Chen H D, Ren J S, Qin C, Xu Y J, Cao W, Wang F, Li J, Tan F W, Dai M, Chen W Q, Li N, He J
Office of Cancer Screening/National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Institute for Chronic and Non-communicable Disease Prevention and Control, Liaoning Provincial Center for Disease Control and Prevention, Shenyang 110005, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2021 May 6;55(5):633-639. doi: 10.3760/cma.j.cn112150-20201015-01286.
To analyze the compliance and related factors of low-dose computed tomography (LDCT) screening among the high-risk population of lung cancer in three provinces participating in the cancer early diagnosis and early treatment program in urban areas of China. From October 2017 to October 2018, 17 983 people aged between 40 and 74 years old at high risk of lung cancer were recruited from Zhejiang, Anhui and Liaoning provinces. The basic demographic characteristics, living habits, history of the disease and family history of cancer were collected by using a cancer risk assessment questionnaire, and the data of participants examined by LDCT were obtained from the hospitals participating in the program. The screening compliance was quantified by the screening participation rate, and it was calculated as the proportion of participants completing LDCT scan among high-risk population. The related factors of LDCT screening compliance were analyzed by using a multivariate logistic regression model. The age of 17 983 participants was (56.52±8.22) years old. Males accounted for 51.9% (N=9 332), and 69.5% (N=12 495) had ever smoked, including former smokers and current smokers. A total of 6 269 participants were screened by LDCT, and the screening participation rate was 34.86%. The results of multivariate logistic regression analysis showed that the age group of 50 to 69 years old, female, passive smokers, alcohol consumption, family history of lung cancer and history of chronic respiratory diseases were more likely to be screened by LDCT, while the compliance of LDCT screening in current smokers was low. The LDCT screening compliance of the high-risk population of lung cancer in urban areas of China still needs to be improved. Age, sex, smoking, drinking, family history of lung cancer and history of chronic respiratory disease are associated with screening compliance.
分析中国城市地区癌症早诊早治项目中三省肺癌高危人群低剂量计算机断层扫描（LDCT）筛查的依从性及相关因素。2017年10月至2018年10月，从浙江、安徽和辽宁省招募了17983名年龄在40至74岁之间的肺癌高危人群。通过癌症风险评估问卷收集基本人口学特征、生活习惯、疾病史和癌症家族史，并从参与该项目的医院获取LDCT检查参与者的数据。筛查依从性通过筛查参与率进行量化，计算方法为高危人群中完成LDCT扫描的参与者比例。采用多因素logistic回归模型分析LDCT筛查依从性的相关因素。17983名参与者的年龄为（56.52±8.22）岁。男性占51.9%（N = 9332），69.5%（N = 12495）曾经吸烟，包括既往吸烟者和当前吸烟者。共有6269名参与者接受了LDCT筛查，筛查参与率为34.86%。多因素logistic回归分析结果显示，50至69岁年龄组、女性、被动吸烟者、饮酒、肺癌家族史和慢性呼吸道疾病史人群更有可能接受LDCT筛查，而当前吸烟者的LDCT筛查依从性较低。中国城市地区肺癌高危人群的LDCT筛查依从性仍有待提高。年龄、性别、吸烟、饮酒、肺癌家族史和慢性呼吸道疾病史与筛查依从性相关。
