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获得性单侧上肢肥大作为结核性脑膜炎并发 Chiari 1 畸形和脊髓空洞症的晚期并发症。

Acquired unilateral upper limb hypertrophy as a late complication of tuberculous meningitis complicated by Chiari 1 malformation and syringomyelia.

机构信息

Paediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, Western Cape, South Africa.

Paediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, Western Cape, South Africa

出版信息

BMJ Case Rep. 2021 May 25;14(5):e240413. doi: 10.1136/bcr-2020-240413.

DOI:10.1136/bcr-2020-240413
PMID:34035015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8154680/
Abstract

Syringomyelia associated with tuberculous meningitis (TBM) is an extremely rare condition. Only a few adult cases have been reported. A 12-year-old woman, who previously suffered TBM at the age of 6 months, presented with a long-standing history of right upper limb panhypertrophy, dissociate anaesthesia, frequent headaches, scoliosis and acquired macrocephaly. MRI demonstrated hydrocephalus, descent of the cerebral tonsils and an intramedullary syrinx extending from C2 to L1. Endoscopic third ventriculostomy (ETV) leads to reduction in the size of the syringomyelia and resolution of the thermoanaesthesia. This case highlights a very rare long-term complication associated with childhood TBM and the potential benefit offered by ETV.

摘要

与结核性脑膜炎(TBM)相关的脊髓空洞症是一种极其罕见的情况。仅有少数成人病例报告。一名 12 岁女性,6 个月时曾患有 TBM,表现为右上肢长期进行性肥大、分离性感觉缺失、频繁头痛、脊柱侧凸和获得性大头畸形。MRI 显示脑积水、大脑扁桃体下降和颈 2 至胸 1 段髓内空洞。内镜第三脑室造瘘术(ETV)可使脊髓空洞缩小,热敏觉缺失缓解。本例突出了与儿童 TBM 相关的一种非常罕见的长期并发症以及 ETV 带来的潜在益处。

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