酒精性肝病的当前管理
Current Management of Alcohol-Associated Liver Disease.
作者信息
Siddiqi Faisal A, Sajja Krishna C, Latt Nyan L
机构信息
Department of Hospital Medicine, Ochsner Medical Center, New Orleans, Louisiana.
Division of Gastroenterology and Hepatology, Ochsner Medical Center, New Orleans, Louisiana.
出版信息
Gastroenterol Hepatol (N Y). 2020 Nov;16(11):561-570.
Abstract
Alcohol consumption is a major risk factor for various diseases worldwide and is one of the most common causes of chronic liver disease. Alcohol use has risen over the past 30 years and is forecast to continue to rise. Concurrently, there has been an increased incidence of alcohol-associated liver disease (ALD). Alcohol use, regardless of the amount, leads to years of health loss across populations when considering the strong association between alcohol consumption and overall disease burden. Given the rising incidence of ALD and associated mortality, it is imperative to study the underlying factors driving these trends. This article summarizes the diagnosis and management of ALD, with a focus on various screening and prognostic tools and treatments for alcohol-associated hepatitis.
摘要
饮酒是全球各种疾病的主要风险因素，也是慢性肝病最常见的病因之一。在过去30年中，饮酒量呈上升趋势，预计还将继续上升。与此同时，酒精性肝病（ALD）的发病率也在增加。考虑到饮酒与总体疾病负担之间的密切关联，无论饮酒量多少，饮酒都会导致人群多年的健康损失。鉴于ALD发病率和相关死亡率不断上升，研究推动这些趋势的潜在因素势在必行。本文总结了ALD的诊断和管理，重点介绍了各种筛查和预后工具以及酒精性肝炎的治疗方法。
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