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Functional Dyspepsia: A Review of the Symptoms, Evaluation, and Treatment Options.

作者信息

Harer Kimberly N, Hasler William L

机构信息

Dr Harer is a clinical lecturer and Dr Hasler is a professor in the Division of Gastroenterology in the University of Michigan Health System in Ann Arbor, Michigan.

出版信息

Gastroenterol Hepatol (N Y). 2020 Feb;16(2):66-74.


DOI:
PMID:34035704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8132673/
Abstract

The community prevalence of dyspepsia ranges from 20% to 40%, and dyspepsia accounts for 3% to 5% of primary care visits. Dyspepsia symptoms include epigastric pain, epigastric burning, postprandial fullness, early satiety, epigastric bloating, nausea, and belching. Functional dyspepsia is diagnosed when an organic etiology for the symptoms is not identified. Diagnostic symptom-based criteria are defined by Rome IV. Functional dyspepsia is further subclassified into postprandial distress syndrome and epigastric pain syndrome based on the predominance of post-prandial bloating and fullness vs epigastric pain. Evaluation of functional dyspepsia is driven by patient age and the presence of red-flag symptoms, such as patients over age 60 years or those with anemia undergoing evaluation with esophagogastroduodenoscopy. infection should be excluded in all patients. Treatment options include proton pump inhibitors, neuromodulators, and prokinetics; however, the evidence supporting these therapies is weak, and the response rate is less than robust.

摘要

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本文引用的文献

[1]
Iberogast-Induced Acute Liver Failure-Reexposure and In Vitro Assay Support Causality.

Am J Gastroenterol. 2019-8

[2]
Female Gender is a Poor Predictive Factor of Functional Dyspepsia Resolution after Eradication: A Prospective, Multi-center Korean Trial.

Korean J Gastroenterol. 2018-12-25

[3]
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Lancet Gastroenterol Hepatol. 2018-10-22

[4]
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Gut. 2019-7

[5]
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Neurogastroenterol Motil. 2018-3-2

[6]
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Neurogastroenterol Motil. 2018-1-8

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Am J Gastroenterol. 2017-12-19

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Cochrane Database Syst Rev. 2017-11-21

[9]
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J Gastroenterol Hepatol. 2018-2

[10]
Clinical characteristics of functional dyspepsia depending on chemosensitivity to capsaicin.

Neurogastroenterol Motil. 2017-5-25

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