Bean Andrew, Al-Bouri Abdullah, Bradford Geoffrey, Mauger Thomas
Department of Ophthalmology and Visual Sciences, West Virginia University School of Medicine, 1 Medical Center Drive, P.O. Box 9193, Morgantown, WV 26506, USA.
Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, WVU Department of Pathology, Room 2187 HSN, P.O. Box 9293, Morgantown, WV 26056, USA.
Case Rep Ophthalmol Med. 2021 May 8;2021:6692229. doi: 10.1155/2021/6692229. eCollection 2021.
Congenital smooth muscle hamartoma is a benign proliferation of smooth muscle that most commonly presents in the lumbosacral area or proximal extremities. Although exceedingly rare, congenital smooth muscle hamartomas have been reported to occur in ocular structures such as the brow, eyelid, and conjunctival fornix. This case describes an atypical congenital bulbar lesion in a newborn male which obscured the cornea. The lesion, which appeared to originate from the bulbar conjunctiva and/or the limbus, was excised at 5 months of age. Pathologic evaluation was consistent with congenital smooth muscle hamartoma. The authors of this report believe it is the first to describe a patient with a congenital smooth muscle hamartoma of the bulbar conjunctiva/limbus.
先天性平滑肌瘤是平滑肌的良性增生，最常见于腰骶部或四肢近端。尽管极为罕见，但先天性平滑肌瘤已有报道发生于眼部结构，如眉部、眼睑和结膜穹窿。本病例描述了一名新生儿男性的非典型先天性球部病变，该病变遮盖了角膜。该病变似乎起源于球结膜和/或角膜缘，在患儿5个月大时切除。病理评估结果符合先天性平滑肌瘤。本报告的作者认为这是首例描述患有球结膜/角膜缘先天性平滑肌瘤患者的病例。
