Huang Hao, Fu Rose H, Vartanian Emma, Du Jerry Y, Otterburn David M
NewYork-Presbyterian, Weill Cornell Medical Center, New York, N.Y.
Oakland Medical Center, Oakland, Calif.
Plast Reconstr Surg Glob Open. 2021 May 21;9(5):e3627. doi: 10.1097/GOX.0000000000003627. eCollection 2021 May.
Although oncologic surgery is deemed urgent during the COVID-19 pandemic, clinical guidelines in reconstructive surgery have been unclear. Utilizing propensity-matched pre-pandemic data and our institutional experience during the crisis, we aimed to assess the safety of immediate device reconstruction following mastectomy to aid in decision-making during the pandemic.
Women undergoing mastectomy only and mastectomy with immediate breast reconstruction (IBR) with tissue expander or permanent implant from the 2007-2013 ACS-NSQIP datasets were included. Multivariate analysis of independent variables was used to form propensity-matched cohorts. Incidence of 30-day major postoperative bleeding and hospital length of stay were compared.
In total, 13,580 mastectomy only patients and 11,636 IBR patients were identified. Factors that were found to be associated with IBR included age ( 0.022), BMI ( 0.001), race ( 0.010), diabetes ( 0.007), chronic steroid use ( 0.003), pulmonary disease ( 0.004), cardiovascular disease ( 0.001), disseminated cancer ( 0.001), chemotherapy before surgery ( 0.016), low hematocrit ( 0.001), and total operative time ( 0.001). After propensity matching, immediate device reconstruction following mastectomy was not found to be associated with greater risk of postoperative bleeding (1.4% versus 1.0%, 0.334) or increased length of stay (1.5 ± 2.9 versus 1.5 ± 3.5 days, 0.576).
Immediate device reconstruction does not elevate morbidity in terms of postoperative bleeding or does not increase the length of hospital exposure. Tissue expander or implant reconstruction can be safely performed immediately following mastectomy during the COVID-19 pandemic. Further, our institutional experience during the pandemic indicates that select patients can continue to safely undergo ambulatory mastectomy with device placement.
尽管在新冠疫情期间肿瘤手术被视为紧急手术,但重建手术的临床指南仍不明确。利用倾向评分匹配的疫情前数据以及我们机构在危机期间的经验,我们旨在评估乳房切除术后即刻进行器械重建的安全性,以协助疫情期间的决策制定。
纳入2007 - 2013年美国外科医师学会国家外科质量改进计划(ACS - NSQIP)数据集中仅接受乳房切除术以及接受乳房切除术后即刻乳房重建(IBR)并使用组织扩张器或永久性植入物的女性患者。使用自变量的多变量分析来形成倾向评分匹配队列。比较术后30天严重出血的发生率和住院时间。
总共识别出13580例仅接受乳房切除术的患者和11636例IBR患者。发现与IBR相关的因素包括年龄(0.022)、体重指数(0.001)、种族(0.010)、糖尿病(0.007)、长期使用类固醇(0.003)、肺部疾病(0.004)、心血管疾病(0.001)、播散性癌症(0.001)、术前化疗(0.016)、低血细胞比容(0.001)和总手术时间(0.001)。倾向评分匹配后,未发现乳房切除术后即刻进行器械重建与术后出血风险增加(1.4%对1.0%,P = 0.334)或住院时间延长(1.5±2.9天对1.5±3.5天,P = 0.576)相关。
即刻器械重建在术后出血方面不会增加发病率,也不会增加住院时间。组织扩张器或植入物重建可在新冠疫情期间乳房切除术后立即安全进行。此外,我们机构在疫情期间的经验表明,部分患者可以继续安全地接受带器械植入的门诊乳房切除术。