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Inoculation of BALB/c mice against Leishmania major infection with Leishmania-derived antigens isolated by gel filtration.

作者信息

Ogunkolade B W, Monjour L, Vouldoukis I, Rhodes-Feuillette A, Frommel D

机构信息

INSERM U 313, Paris, France.

出版信息

J Chromatogr. 1988 May 25;440:459-65. doi: 10.1016/s0021-9673(00)94550-3.

DOI:10.1016/s0021-9673(00)94550-3
PMID:3403672
Abstract

Gel filtration can be used as a substitute for preparative polyacrylamide gel electrophoresis in the preparation of an immunogenic, partly purified, fraction isolated from lysates of Leishmania promastigotes. This fraction, the molecular weight of which ranged from 70,000 to 53,000, when administered to BALB/c mice in associated with muramyl dipeptide induced resistance against cutaneous leishmaniasis.

摘要

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