Department of Mechanical Engineering, Maulana Azad National Institute of Technology, Bhopal-462003, India.
Biomed Phys Eng Express. 2021 May 26;7(4). doi: 10.1088/2057-1976/ac00d1.
Screws made up of non-biodegradable materials (Ti-alloy, etc.) have been used since long for temporary joining/fixation in applications involving skeleton damage or bone fracture. These screws need to be removed after complete healing as their sustained presence results in many complications, such as - micro-fracturing, stress shielding, etc. The removal of these screws is a little difficult too as it may result in the healed bone getting broken/damaged again. These problems can be overcome by employing metallic implants (plate, screws, etc.) made up of biodegradable metallic materials (Mg-alloy, etc.). Such implants exhibit optimal mechanical performance, are biocompatible, have adequate biodegradation rates, and rely on a unique design. Internal fracture fixation makes usage of screws with or without an accompanying plate. Buttress-threaded screws are the most frequently used ones. These screws must have the capacity to bear usually occurring loads and hold fractured segments of bone all through the process of healing. Finite element analysis (FEA) is an effective technique used for testing and validation of desired characteristics for Mg-based biodegradable buttress-threaded screw (BBTS). The characteristics of interest include maximum possible pullout resistance to tightly hold segments of bone, torsional ability for tightening or tapping, bending ability during providing plate support by screw head, and resistance to combined loading (tensile/compressive and bending) during the self-support stage using merely the screw(s). According to test results and subsequent validation through discretization error and convergence plot, BBTS made up of Mg-alloy are found safe for regular applications under usually encountered impact loads. Topological optimization and vibration analysis are also performed wherein it is observed that design of BBTS is good enough for possible usage in fracture fixation in orthopaedics.
自很久以前以来,由不可生物降解材料(钛合金等)制成的螺钉就一直被用于涉及骨骼损伤或骨折的应用中的临时连接/固定。由于它们的持续存在会导致许多并发症,例如微骨折、应力屏蔽等,因此在完全愈合后需要将这些螺钉取出。由于这些螺钉的取出也有点困难,可能会导致已愈合的骨头再次断裂/损坏。通过使用由可生物降解金属材料(镁合金等)制成的金属植入物(板、螺钉等)可以克服这些问题。这些植入物具有最佳的机械性能、生物相容性、适当的降解率,并依赖于独特的设计。内部骨折固定使用带有或不带有配套板的螺钉。带有螺纹的支撑螺钉是最常用的。这些螺钉必须具有承受通常发生的负载的能力,并在整个愈合过程中保持骨折骨段的固定。有限元分析(FEA)是一种用于测试和验证基于 Mg 的可生物降解支撑螺纹螺钉(BBTS)所需特性的有效技术。感兴趣的特性包括尽可能大的抗拔出阻力以紧紧固定骨段、用于拧紧或攻丝的扭转能力、通过螺钉头提供板支撑时的弯曲能力以及在仅使用螺钉的情况下在自支撑阶段抵抗组合加载(拉伸/压缩和弯曲)的能力。根据测试结果以及通过离散化误差和收敛图进行的后续验证,发现由镁合金制成的 BBTS 在通常遇到的冲击载荷下可安全用于常规应用。还进行了拓扑优化和振动分析,从中可以观察到 BBTS 的设计足以用于骨科骨折固定中的可能用途。