Durand D, Bauchart D, Lefaivre J, Donnat J P
Laboratoire d'Etude du Métabolisme Energétique, Institut National de la Recherche Agronomique de Theix, Ceyrat, France.
J Dairy Sci. 1988 Jun;71(6):1632-7. doi: 10.3168/jds.S0022-0302(88)79727-1.
A method of continuous in vivo flow measurement of plasma metabolites through the liver in calves was described. Five 2-wk old male calves were fitted with chronic catheters in the hepatic and portal veins and in the hepatic artery and with electromagnetic blood flow probes in the portal vein and in the hepatic artery. The reliability of measurements was tested during a 3-wk period in which calves were fed milk diets that curdled or did not curdle (uncurdled) in the abomasum. In comparison with a conventional curdled milk diet, the intake of uncurdled milk diet did not modify mean portal vein (47 to 49 ml.mn-1.kg live weight-1) or hepatic arterial (5.6 to 5.7 ml.mn-1.kg live weight-1) blood flows but did influence nycthemeral variations in portal blood flow rates, especially during the second part of the night.
描述了一种在小牛体内连续测量通过肝脏的血浆代谢物流量的方法。五只2周龄的雄性小牛在肝静脉、门静脉、肝动脉中植入了慢性导管,并在门静脉和肝动脉中安装了电磁血流探头。在为期3周的时间里,给小牛喂食在皱胃中会凝结或不会凝结(未凝结)的牛奶日粮,以此测试测量的可靠性。与传统的凝结牛奶日粮相比,未凝结牛奶日粮的摄入量并未改变门静脉平均血流量(47至49毫升·分钟-1·千克体重-1)或肝动脉血流量(5.6至5.7毫升·分钟-1·千克体重-1),但确实影响了门静脉血流速率的昼夜变化,尤其是在夜间的后半段。