Department of Internal Medicine, King Hussein Cancer Center, Amman, Jordan.
School of Medicine, University of Jordan, Amman, Jordan.
J Int Med Res. 2021 May;49(5):3000605211018448. doi: 10.1177/03000605211018448.
The crisis in Syria has had a profound impact on the entire region. In this study, we report the patterns of presentation and management of Syrian patients with breast cancer treated at our institution.
We retrospectively collected data on Syrian refugees treated for breast cancer over the past 10 years at our center. Management was compared against our approved clinical practice guidelines.
A total of 113 patients were eligible and included. The median age (range) at diagnosis was 47 (21-84) years and most women presented with locally advanced or metastatic disease (n = 74, 65.5%). Breast-conserving surgery and breast reconstruction were performed in 27 (33.8%) and 11 (35.4%) patients, respectively. Only a few patients received targeted (35.5%) or advanced endocrine therapy (30.0%). In total, 37 (32.7%) patients had considerable deviations from our institutional treatment guidelines and had worse outcomes.
Syrian refugees with breast cancer present late, have more advanced-stage disease, and are more likely to receive delayed and suboptimal therapy. An international systematic approach for cancer care among such vulnerable populations is urgently needed.
叙利亚危机对整个地区产生了深远的影响。在本研究中，我们报告了在我们机构接受治疗的叙利亚乳腺癌患者的表现和治疗模式。
我们回顾性地收集了过去 10 年在我们中心接受乳腺癌治疗的叙利亚难民患者的数据。将管理与我们批准的临床实践指南进行了比较。
共有 113 名符合条件的患者入选。诊断时的中位年龄（范围）为 47 岁（21-84 岁），大多数女性表现为局部晚期或转移性疾病（n=74，65.5%）。27 名（33.8%）患者接受了保乳手术，11 名（35.4%）患者接受了乳房重建。只有少数患者接受了靶向治疗（35.5%）或高级内分泌治疗（30.0%）。共有 37 名（32.7%）患者严重偏离了我们的机构治疗指南，预后更差。
患有乳腺癌的叙利亚难民就诊较晚，疾病分期更晚，更有可能接受延迟和不充分的治疗。迫切需要对这些弱势群体进行癌症护理的国际系统性方法。
