Ophthalmic Surg Lasers Imaging Retina. 2021 Mar;52(3):160-164. doi: 10.3928/23258160-20210302-08. Epub 2021 Mar 1.
Although a small number of cases of secondary uveitis have been documented in the setting of ibrutinib therapy, panuveitis has not previously been described with this medication. The authors describe a presumed case of panuveitis in a patient on ibrutinib for chronic lymphocytic leukemia. The purpose of this report is to document a case of asymmetric, bilateral panuveitis in the setting of ibrutinib use. Panuveitis may develop in the setting of ibrutinib use, and local steroid therapy can be successfully used for treatment without cessation of systemic cancer therapy. .
虽然在伊布替尼治疗中已经有少数继发性虹膜炎的病例被记录,但以前尚未描述过这种药物引起的全葡萄膜炎。作者描述了一例慢性淋巴细胞白血病患者在使用伊布替尼时发生的疑似全葡萄膜炎。本报告的目的是记录一例在使用伊布替尼的情况下发生的不对称性双侧全葡萄膜炎。在使用伊布替尼的情况下可能会发生全葡萄膜炎,局部类固醇治疗可成功用于治疗,而无需停止全身癌症治疗。