Ibrahim Bilal, Muhsen Baha'eddin A, Najera Edinson, Borghei-Razavi Hamid, Adada Badih
Department of Neurosurgery, Braathen Center, Cleveland Clinic Florida, Weston, FL, USA.
Ann Med Surg (Lond). 2021 Apr 15;66:102308. doi: 10.1016/j.amsu.2021.102308. eCollection 2021 Jun.
Classic trigeminal neuralgia (TN) is caused by vessels compressing the trigeminal nerve root entry zone. The cause is usually impingement of the superior cerebellar artery, anterior inferior cerebellar artery, or a vein. Other rare causes have been reported including aneurysmal compression, skull base tumors, and vascular malformations. An enlarged suprameatal tubercle (EST) as a cause of TN has not yet been described.
We report the first case of 37 year old female patient presented with severe TN involving the three branches of trigeminal nerve who failed medical treatment and underwent multiple balloon compression for left TN with minimal improvement. The severity of pain was assessed using Barrow Neurological Institute (BNI) pain intensity score. Patient had brain MRI with CISS sequence and CT scan for the brain. After careful revision of her imaging studies, patient found to have prominent and heavily calcified left supra meatal tubercle. Her preoperative BNI score was 5.Patient had left retrosigmoid craniotomy and drilling of left suprameatal tubercle. No other structures were seen in contact with left trigeminal nerve root entry zone. Patient had significant improvement on her pain, postoperative BNI score was 1 until the last follow-up 4 years.
EST is a rare cause of TGN and should be suspected as the offending compressing structure when no other causes seen on imaging studies.
经典型三叉神经痛(TN)是由血管压迫三叉神经根入区所致。其病因通常是小脑上动脉、小脑前下动脉或静脉的压迫。其他罕见病因也有报道,包括动脉瘤压迫、颅底肿瘤和血管畸形。尚未有将扩大的颞骨岩部上结节(EST)作为TN病因的描述。
我们报告首例37岁女性患者,患有累及三叉神经三个分支的严重TN,药物治疗无效,接受多次球囊压迫治疗左侧TN,但改善甚微。使用巴罗神经学研究所(BNI)疼痛强度评分评估疼痛严重程度。患者进行了脑部磁共振成像(MRI)的稳态构成干扰序列(CISS)检查及脑部CT扫描。在仔细复查其影像学检查后,发现患者左侧颞骨岩部上结节突出且钙化严重。其术前BNI评分为5分。患者接受了左侧乙状窦后开颅术及左侧颞骨岩部上结节钻孔术。未发现其他结构与左侧三叉神经根入区接触。患者疼痛明显改善,术后BNI评分直至4年的最后一次随访时均为1分。
EST是TGN的罕见病因,当影像学检查未发现其他病因时,应怀疑其为造成压迫的病变结构。