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用N-异丙基-p-[123I] - 碘安非他明对眼黑色素瘤进行可视化成像。

Visualization of ocular melanoma with N-isopropyl-p-[123I]-iodoamphetamine.

作者信息

Ono S, Fukunaga M, Otsuka N, Nagai K, Morita K, Furukawa T, Muranaka A, Yanagimoto S, Tomomitsu T, Tabuchi A

机构信息

Department of Nuclear Medicine and Ophthalmology, Kawasaki Medical School, Kurashiki, Japan.

出版信息

J Nucl Med. 1988 Aug;29(8):1448-50.

PMID:3404259
Abstract

In a patient with ocular melanoma, scintigraphy with N-isopropyl-p-[123I]-iodoamphetamine [( 123I]IMP) clearly delineated the histologically proven ocular lesion. In a tissue distribution study, using the resected specimen, a significantly high accumulation of the radioactivity was confirmed in tumor tissue. Thus, [123I]IMP scintigraphy provided specific localization of an ocular melanoma.

摘要

在一名眼黑色素瘤患者中,用N-异丙基-p-[123I]-碘安非他明[(123I]IMP)进行闪烁扫描清晰地描绘出了经组织学证实的眼部病变。在一项使用切除标本的组织分布研究中,证实肿瘤组织中放射性物质有显著的高积聚。因此,[123I]IMP闪烁扫描可对眼黑色素瘤进行特异性定位。

相似文献

1
Visualization of ocular melanoma with N-isopropyl-p-[123I]-iodoamphetamine.用N-异丙基-p-[123I] - 碘安非他明对眼黑色素瘤进行可视化成像。
J Nucl Med. 1988 Aug;29(8):1448-50.
2
[123I-N-isopropyl-p-iodoamphetamine scintigraphy in patients with malignant melanoma].[123I-N-异丙基-对碘安非他明闪烁扫描术用于恶性黑色素瘤患者]
Radioisotopes. 1990 Apr;39(4):163-7. doi: 10.3769/radioisotopes.39.4_163.
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[Scintigraphy using N-isopropyl-p-[123I]-iodoamphetamine in malignant melanoma].[利用 N-异丙基-p-[123I]-碘安非他明进行恶性黑色素瘤的闪烁扫描术]
Kaku Igaku. 1988 Oct;25(10):1149-53.
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[Visualization of bone marrow with N-isopropyl-p-[123I]-iodoamphetamine in a case of malignant melanoma].[用 N-异丙基-p-[123I]-碘安非他明对一例恶性黑色素瘤患者的骨髓进行显像]
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Scintigraphic visualization of human malignant melanoma with N-isopropyl-P-[I-123] iodoamphetamine.用 N-异丙基-P-[I-123] 碘安非他明对人类恶性黑色素瘤进行闪烁显像。
Clin Nucl Med. 1985 Jun;10(6):415-7. doi: 10.1097/00003072-198506000-00008.
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[A case of choroidal malignant melanoma in which 123I-IMP scintigraphy was useful for diagnosis].[123I-IMP闪烁扫描术有助于诊断的脉络膜恶性黑色素瘤病例]
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[Visualization of a lung metastatic lesion from malignant melanoma by N-isopropyl-p-123I-iodoamphetamine: usefulness of L-dopa load scintigraphy].[N-异丙基-p-123I-碘安非他明对恶性黑色素瘤肺转移灶的可视化:左旋多巴负荷闪烁扫描的效用]
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Scintigraphic study of malignant melanoma with 123I-iodoamphetamine.用123I-碘安非他明对恶性黑色素瘤进行闪烁扫描研究。
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Increased accumulation of N-isopropyl-(I-123)p-iodoamphetamine in bronchial carcinoid tumor.
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引用本文的文献

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Accumulation of N-Isopropyl-p(123I)iodoamphetamine on Single-Photon Emission Computed Tomography Between Immunosuppressed and Non-immunosuppressed Patients With Primary Central Nervous System Lymphoma.原发性中枢神经系统淋巴瘤免疫抑制和非免疫抑制患者单光子发射计算机断层扫描中 N-异丙基-p(123I)碘安非他明的蓄积情况
Cureus. 2025 Apr 22;17(4):e82763. doi: 10.7759/cureus.82763. eCollection 2025 Apr.
2
Design, synthesis, and preliminary in vitro and in vivo evaluation of N-(2-diethylaminoethyl)-4-[18F]fluorobenzamide ([18F]-DAFBA): a novel potential PET probe to image melanoma tumors.设计、合成、初步的体外和体内评价 N-(2-二乙氨基乙基)-4-[18F]氟苯甲酰胺([18F]-DAFBA):一种新型潜在的 PET 探针,用于成像黑色素瘤肿瘤。
Bioconjug Chem. 2009 Mar 18;20(3):583-90. doi: 10.1021/bc8005094.
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Diagnosis of atypical choroidal malignant melanoma using N-isopropyl-p-[123I]-iodoamphetamine single photon emission computed tomography.使用N-异丙基-p-[123I]-碘安非他明单光子发射计算机断层扫描诊断非典型脉络膜恶性黑色素瘤。
Jpn J Ophthalmol. 2006 Mar-Apr;50(2):185-7. doi: 10.1007/s10384-005-0280-2.
4
Possibilities and limitations of radioimmunoscintigraphy and conventional diagnostic modalities in choroidal melanoma.放射性免疫闪烁造影术与传统诊断方法在脉络膜黑色素瘤中的应用可能性及局限性
Br J Ophthalmol. 1994 Apr;78(4):244-8. doi: 10.1136/bjo.78.4.244.