用N-异丙基-p-[123I] - 碘安非他明对眼黑色素瘤进行可视化成像。

Visualization of ocular melanoma with N-isopropyl-p-[123I]-iodoamphetamine.

作者信息

Ono S, Fukunaga M, Otsuka N, Nagai K, Morita K, Furukawa T, Muranaka A, Yanagimoto S, Tomomitsu T, Tabuchi A

机构信息

Department of Nuclear Medicine and Ophthalmology, Kawasaki Medical School, Kurashiki, Japan.

出版信息

J Nucl Med. 1988 Aug;29(8):1448-50.

Abstract

In a patient with ocular melanoma, scintigraphy with N-isopropyl-p-[123I]-iodoamphetamine [( 123I]IMP) clearly delineated the histologically proven ocular lesion. In a tissue distribution study, using the resected specimen, a significantly high accumulation of the radioactivity was confirmed in tumor tissue. Thus, [123I]IMP scintigraphy provided specific localization of an ocular melanoma.

摘要

在一名眼黑色素瘤患者中，用N-异丙基-p-[123I]-碘安非他明[（123I]IMP）进行闪烁扫描清晰地描绘出了经组织学证实的眼部病变。在一项使用切除标本的组织分布研究中，证实肿瘤组织中放射性物质有显著的高积聚。因此，[123I]IMP闪烁扫描可对眼黑色素瘤进行特异性定位。

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