阴性血清型关节炎作为惠普尔病的一种并发症
Seronegative Arthritis as a Complication of Whipple's Disease.
作者信息
DeBoer Rebecca, Jayatilaka Sahani, Donato Anthony
机构信息
Department of Medicine, Reading Hospital, Reading, PA, USA.
出版信息
Clin Med Insights Case Rep. 2021 May 17;14:11795476211017717. doi: 10.1177/11795476211017717. eCollection 2021.
Abstract
Whipple's disease (WD) is an uncommon cause of seronegative arthritis. WD is known for its gastrointestinal symptoms of diarrhea, weight loss, and abdominal pain. However, arthritis may precede gastrointestinal symptoms by 6 to 7 years. We describe a case of an 85-year-old Caucasian male with multiple joint complaints, not responsive to traditional treatments for conditions such as rheumatoid arthritis and osteoarthritis. We suggest that WD be considered for seronegative arthritis especially affecting large joints.
摘要
惠普尔病（WD）是血清阴性关节炎的一种罕见病因。WD以腹泻、体重减轻和腹痛等胃肠道症状而闻名。然而，关节炎可能比胃肠道症状提前6至7年出现。我们描述了一例85岁的白种男性病例，他有多处关节不适，对类风湿关节炎和骨关节炎等疾病的传统治疗无反应。我们建议，对于特别是累及大关节的血清阴性关节炎，应考虑惠普尔病。
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