Santoni Matteo, Tombesi Francesco, Cimadamore Alessia, Montironi Rodolfo, Piva Francesco
Oncology Unit, Macerata Hospital, Macerata, Italy.
Physics Department, University of Rome "Tor Vergata", Rome, Italy.
Front Oncol. 2021 May 11;11:634818. doi: 10.3389/fonc.2021.634818. eCollection 2021.
Adopting three physically-motivated scales ("micro" - "meso" - "macro", which refer to mpc - kpc - Mpc, respectively) is paramount for achieving a unified theory of multiphase active galactic nuclei feeding and feedback, and it represents a keystone for astrophysical simulations and observations in the upcoming years. In order to promote this multi-scale idea, we have decided to adopt an interdisciplinary approach, exploring the possible conceptual similarities between supermassive black hole feeding and feedback cycles and the dynamics occurring in human cancer microenvironment.
采用三种基于物理的尺度(“微观”——“中观”——“宏观”,分别对应毫秒差距——千秒差距——百万秒差距)对于实现多相活动星系核吸积与反馈的统一理论至关重要,并且它是未来几年天体物理模拟与观测的关键。为了推广这种多尺度理念,我们决定采用跨学科方法,探索超大质量黑洞吸积与反馈循环和人类癌症微环境中发生的动力学之间可能存在的概念相似性。