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对戒烟治疗与干预的系统评价和荟萃分析摘要中自旋的评估。

Evaluation of spin in the abstracts of systematic reviews and meta-analyses of treatments and interventions for smoking cessation.

作者信息

Garrett Morgan, Koochin Tremayne, Ottwell Ryan, Arthur Wade, Rogers Taylor C, Hartwell Micah, Chen Elizabeth, Ford Alicia, Wright Drew N, Sealey Meghan, Zhu Lan, Vassar Matt

机构信息

Office of Medical Student Research, Center for Health Sciences, Oklahoma State University, Tulsa, United States.

College of Osteopathic Medicine, Kansas City University of Medicine and Biosciences, Joplin, United States.

出版信息

Tob Prev Cessat. 2021 May 20;7:35. doi: 10.18332/tpc/134238. eCollection 2021.

Abstract

INTRODUCTION

Smoking cessation treatments and available evidence continue to evolve. To stay current with the latest research, physicians often refer to abstracts of systematic reviews. Because abstracts of systematic reviews may have direct effects on patient care, the information within them should be free of 'spin'. Spin is a specific way of reporting, intentional or not, to highlight that the beneficial effect of the experimental treatment in terms of efficacy or safety is greater than that shown by the results (i.e. overstate efficacy and/or understate harm).

METHODS

We searched systematic reviews and meta-analyses focused on interventions and treatments for smoking cessation. Full-text screening, data extraction, evaluation of spin, and quality assessment were conducted in masked, duplicate fashion. Study and journal characteristics were also recorded to determine whether they were associated with the presence of spin.

RESULTS

A total of 200 systematic reviews that met inclusion criteria were included in the final analyses. Spin occurred in 3.5% (7/200) of the systematic review abstracts included in our sample. No study characteristics were significantly associated with spin.

CONCLUSIONS

Of the reviewed abstracts in systematic reviews and meta-analyses, 96.5% of those that focused on smoking cessation were free of spin. However, the existence of spin warrants further steps to improve the scientific accuracy of abstracts on smoking cessation treatments. By identifying and acknowledging the presence of spin in systematic reviews, we hope to increase awareness about reporting practices in an ultimate effort to improve the integrity of scientific research as a whole.

摘要

引言

戒烟治疗方法和现有证据不断发展。为了紧跟最新研究成果,医生们常常参考系统评价的摘要。由于系统评价的摘要可能会对患者护理产生直接影响,其中的信息应避免“倾向性表述”。倾向性表述是一种特定的报告方式,无论是否有意,旨在突出实验性治疗在疗效或安全性方面的有益效果大于结果所示(即夸大疗效和/或低估危害)。

方法

我们检索了聚焦于戒烟干预措施和治疗方法的系统评价和荟萃分析。采用双盲、重复的方式进行全文筛选、数据提取、倾向性表述评估和质量评估。还记录了研究和期刊的特征,以确定它们是否与倾向性表述的存在有关。

结果

最终分析纳入了总共200篇符合纳入标准的系统评价。在我们样本中的系统评价摘要中,3.5%(7/200)存在倾向性表述。没有研究特征与倾向性表述显著相关。

结论

在系统评价和荟萃分析中经过评审的摘要里,96.5%聚焦于戒烟的摘要没有倾向性表述。然而,倾向性表述的存在值得采取进一步措施来提高戒烟治疗摘要的科学准确性。通过识别和承认系统评价中倾向性表述的存在,我们希望提高对报告做法的认识,最终努力提高整个科学研究的诚信度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704c/8135573/b87382901f24/TPC-7-35-g001.jpg

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